Evidence map›Paper›PMID 32483135›Full record

ArticleNature communications2020

Chronic expression of p16

Narmen Azazmeh, Benjamin Assouline, Eitan Winter, Shmuel Ruppo, Yuval Nevo, Alexander Maly, Karen Meir, Agnieszka K Witkiewicz, Jonathan Cohen, Sophia V Rizou and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Signaling pathways and targeted interventions for precancers.Signal transduction and targeted therapy · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. RSK3 switches cell fate: from stress-induced senescence to malignant progression.Journal of experimental & clinical cancer research : CR · 2023
    Article
  18. Article
  19. Non-Genomic Hallmarks of Aging-The Review.International journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Narmen AzazmehDepartment of Developmental Biology and Cancer Research, Institute for Medical Research - Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Benjamin AssoulineDepartment of Developmental Biology and Cancer Research, Institute for Medical Research - Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Eitan WinterInfo-CORE, Bioinformatics Unit of the I-CORE Computation Center at the Hebrew University and Hadassah, Jerusalem, Israel.
Shmuel RuppoInfo-CORE, Bioinformatics Unit of the I-CORE Computation Center at the Hebrew University and Hadassah, Jerusalem, Israel.
Yuval NevoInfo-CORE, Bioinformatics Unit of the I-CORE Computation Center at the Hebrew University and Hadassah, Jerusalem, Israel.
Alexander MalyDepartment of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Karen MeirDepartment of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Agnieszka K WitkiewiczRoswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, USA.
Jonathan CohenDepartment of Cell and Developmental Biology, Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel.
Sophia V RizouDepartment of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Eli PikarskyDepartment of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Chen LuxenburgDepartment of Cell and Developmental Biology, Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel.
Vassilis G GorgoulisDepartment of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0001-9001-4112
Ittai Ben-PorathDepartment of Developmental Biology and Cancer Research, Institute for Medical Research - Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel. ittaibp@mail.huji.ac.il.ORCID http://orcid.org/0000-0001-7815-1165
Hebrew University of Jerusalem · ILIsraeli Centers for Research Excellence · ILHadassah Medical Center · ILNational and Kapodistrian University of Athens · GRTel Aviv University · ILRoswell Park Comprehensive Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

p16

Indexed as

AnimalsCell ProliferationCells, CulturedCell Transformation, NeoplasticCyclin-Dependent Kinase Inhibitor p16EpidermisHumansHyperplasiaKeratinocytesKeratosisMice, 129 StrainMice, Inbred C57BLMice, TransgenicPapillomaWnt Signaling PathwayCyclin-Dependent Kinase Inhibitor p16

Identifiers

PMID32483135
PMCPMC7264228
OpenAlexW3031553099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.