Evidence map›Paper›PMID 32482938›Full record

ArticleJournal of microbiology and biotechnology2019

In Vitro Characterization of Lactic Acid Bacteria from Indonesian Kefir Grains as Probiotics with Cholesterol-Lowering Effect.

Dandy Yusuf, Lilis Nuraida, Ratih Dewanti-Hariyadi, Dase Hunaefi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. In Silico Prediction of Bioactive Peptides FromInternational journal of microbiology · 2026
    Article
  3. Kefir revisited: Insights from the North Caucasus.World journal of experimental medicine · 2025
    Review
  4. Investigation of Probiotic Properties ofFood science & nutrition · 2025
    Article
  5. Article
  6. Article
  7. Potential of White Jack Bean (Preventive nutrition and food science · 2023
    Article
  8. Article
  9. Article
  10. Probiotic ofFoods (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Kefir and Its Biological Activities.Foods (Basel, Switzerland) · 2021
    Review
  17. Construction and Analysis of Food-GradeJournal of microbiology and biotechnology · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dandy YusufDepartment of Food Science and Technology, Faculty of Agricultural Technology, IPB University (Bogor Agricultural University), Bogor, West Java, Indonesia.
Lilis NuraidaDepartment of Food Science and Technology, Faculty of Agricultural Technology, IPB University (Bogor Agricultural University), Bogor, West Java, Indonesia.
Ratih Dewanti-HariyadiDepartment of Food Science and Technology, Faculty of Agricultural Technology, IPB University (Bogor Agricultural University), Bogor, West Java, Indonesia.
Dase HunaefiDepartment of Food Science and Technology, Faculty of Agricultural Technology, IPB University (Bogor Agricultural University), Bogor, West Java, Indonesia.
IPB University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indonesian kefir grains are potential sources of lactic acid bacteria (LAB) that may act as probiotics with specific functional properties. In this study we explored the potential of the probiotic and cholesterol-lowering effect of LAB isolated from Indonesian kefir grains obtained from Bogor, Bandung, Jakarta, and Yogyakarta. The results revealed that 10 isolates showed considerable survivability at low pH and bile salt with total cell reduction of ~3 log colony-forming units per milliliter after exposure to pH 2.5 and 0.5% (w/v) bile salt for 1 and 3 h, respectively. All strains exhibited strong antimicrobial activities against pathogenic bacteria and were sensitive to a wide spectrum of antibiotics but exhibited weak bile salt hydrolase activity. Identification based on 16S RNA suggested that nine isolates were

Indexed as

Anti-Bacterial AgentsAntibiosisBile Acids and SaltsCholesterolCluster AnalysisDNA, BacterialDNA, RibosomalHydrogen-Ion ConcentrationHydrolasesIndonesiaKefirLacticaseibacillus rhamnosusLactobacillusMicrobial ViabilityPhylogenyProbioticsAnti-Bacterial AgentsBile Acids and SaltsCholesterolDNA, BacterialDNA, RibosomalHydrolasesRNA, Ribosomal, 16SCholesterolkefir grainslactic acid bacteriaLactobacillusprobiotics

Identifiers

PMID32482938
PMCPMC9728407
OpenAlexW3010868197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.