Evidence map›Paper›PMID 32482892›Full record

ArticleThe Journal of biological chemistry2020

Group V secreted phospholipase A

Kazuhiro Watanabe, Yoshitaka Taketomi, Yoshimi Miki, Kiyotaka Kugiyama, Makoto Murakami

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Secreted phospholipase PLA2G5 acts as a hemolytic factor in sepsis.The Journal of clinical investigation · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Progress and perspectives of metabolic biomarkers in human aortic dissection.Metabolomics : Official journal of the Metabolomic Society · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Arterial dissections: Common features and new perspectives.Frontiers in cardiovascular medicine · 2022
    Review
  11. Article
  12. Article
  13. Updating Phospholipase ABiomolecules · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kazuhiro WatanabeDepartment of Internal Medicine II, University of Yamanashi, Department of Internal Medicine II, Chuo, Yamanashi Japan.ORCID 0000-0003-4056-2991
Yoshitaka TaketomiLipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Yoshimi MikiLipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.ORCID 0000-0002-8587-0333
Kiyotaka KugiyamaDepartment of Internal Medicine II, University of Yamanashi, Department of Internal Medicine II, Chuo, Yamanashi Japan kugiyama@yamanashi.ac.jp makmurak@m.u-tokyo.ac.jp.
Makoto MurakamiLipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan kugiyama@yamanashi.ac.jp makmurak@m.u-tokyo.ac.jp.ORCID 0000-0002-4565-6017
Tokyo Metropolitan Institute of Medical Science · JPJapan Agency for Medical Research and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic dissection is a life-threatening aortopathy involving separation of the aortic wall, whose underlying mechanisms are still incompletely understood. Epidemiological evidence suggests that unsaturated fatty acids improve cardiovascular health. Here, using quantitative RT-PCR, histological analyses, magnetic cell sorting and flow cytometry assays, and MS-based lipidomics, we show that the activity of a lipid-metabolizing enzyme, secreted phospholipase A

Indexed as

Endoplasmic Reticulum StressAngiotensin IIAnimalsAortaAortic DissectionDisease Models, AnimalGroup V Phospholipases A2Linoleic AcidMiceMice, KnockoutOleic AcidPhospholipidsAngiotensin IIGroup V Phospholipases A2Linoleic AcidOleic AcidPhospholipidsanimal modelaortic dissectionaortopathycardiovascular diseasecardiovascular disorderextracellular matrixfatty acidgene knockoutlipidomicslysyl oxidasephospholipasephospholipase A2phospholipid metabolism

Identifiers

PMID32482892
PMCPMC7383374
OpenAlexW3029069345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.