Evidence map›Paper›PMID 32482837›Full record

ArticleThorax2020

Skeletal muscle adiposity and outcomes in candidates for lung transplantation: a lung transplant body composition cohort study.

Michaela R Anderson, Imaani Easthausen, Grace Gallagher, Jayaram Udupa, Yubing Tong, Drew Torigian, Joshua Matthew Diamond, Mary Katherine Porteous, Scott M Palmer, Laurie D Snyder and 14 more

Abstract read
In one paragraph

Article in Thorax, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Optimal computed tomography-based biomarkers for prediction of incisional hernia formation.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Development of the Lung Transplant Frailty Scale (LT-FS).The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  10. European Society of Organ Transplantation (ESOT) Consensus Statement on Prehabilitation for Solid Organ Transplantation Candidates.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Michaela R AndersonMedicine, Columbia University Medical Center, New York, New York, USA mdr2140@cumc.columbia.edu.
Imaani EasthausenPopulation Health Sciences, Weill Cornell Medical College, New York, New York, USA.
Grace GallagherMedicine, Columbia University Medical Center, New York, New York, USA.
Jayaram UdupaRadiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yubing TongRadiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Drew TorigianRadiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joshua Matthew DiamondPulmonary, Allergy, and Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Mary Katherine PorteousPulmonary, Allergy, and Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Scott M PalmerMedicine, Duke University, Durham, North Carolina, USA.
Laurie D SnyderMedicine, Duke University, Durham, North Carolina, USA.
Luke BenvenutoMedicine, Columbia University Medical Center, New York, New York, USA.
Meghan AversaMedicine, Columbia University Medical Center, New York, New York, USA.
Selim ArcasoyMedicine, Columbia University Medical Center, New York, New York, USA.
John R GreenlandMedicine, VA Medical Center, San Francisco, California, USA.ORCID 0000-0003-1422-8367
Steven R HaysMedicine, University of California, San Francisco, California, USA.
Jasleen KukrejaSurgery, University of California, San Francisco, California, USA.
Edward CantuRadiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
John Shinn KimMedicine, University of Virginia School of Medicine, Charlottesville, Virginia, USA.ORCID 0000-0002-8887-150X
Dympna GallagherMedicine, Columbia University Medical Center, New York, New York, USA.
Matthew R BaldwinMedicine, Columbia University Medical Center, New York, New York, USA.ORCID 0000-0003-4670-3433
R Graham BarrMedicine, Columbia University Medical Center, New York, New York, USA.
David J LedererMedicine, Columbia University Medical Center, New York, New York, USA.ORCID 0000-0001-5258-0228
Jason D ChristieRadiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jonathan Paul SingerMedicine, University of California, San Francisco, California, USA.ORCID 0000-0003-0224-7472

Funding

Clinical Risk Factors for Primary Graft DysfunctionR01HL087115 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2007 to 2017
$7.1M
The Columbia University Training Program in Lung ScienceT32HL105323 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jahar Bhattacharya, Wellington V. Cardoso · 2011 to 2026
$4.7M
Frailty and patient centered outcomes in candidates for lung transplantationR01HL134851 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SINGER, JONATHAN PAUL · 2017 to 2021
$3.4M
Obesity, Inflammation, and Lung Injury After Lung TransplantationR01HL114626 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHRISTIE, JASON D, LEDERER, DAVID J. · 2013 to 2016
$3.1M
Mentored Patient Oriented Research in Lung TransplantationK24HL115354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2012 to 2021
$1.2M
Mentored Patient Oriented Research in Pulmonary Fibrosis and Lung TransplantationK24HL131937 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEDERER, DAVID J. · 2016 to 2018
$352k
Immune Mechanisms of Large-airway Lymphocytic BronchitisIK2CX001034 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI GREENLAND, JOHN · 2015 to 2019
–
Cytomegalovirus Immune Responses in Chronic Lung Allograft Dysfunction PathogenesisI01CX002011 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI GREENLAND, JOHN · 2020 to 2025
–
CSRD VA I01 CX002011CSRD VA IK2 CX001034NHLBI NIH HHS K24 HL115354NHLBI NIH HHS K24 HL131937NHLBI NIH HHS L30 HL143645NHLBI NIH HHS R01 HL087115NHLBI NIH HHS R01 HL114626NHLBI NIH HHS R01 HL134851NHLBI NIH HHS T32 HL105323
6 · The paper itself

Abstract

CT measurement of body composition may improve lung transplant candidate selection. We assessed whether skeletal muscle adipose deposition on abdominal and thigh CT scans was associated with 6 min walk distance (6MWD) and wait-list survival in lung transplant candidates. Each ½-SD decrease in abdominal muscle attenuation (indicating greater lipid content) was associated with 14 m decrease in 6MWD (95% CI -20 to -8) and 20% increased risk of death or delisting (95% CI 10% to 40%). Each ½-standard deviation decrease in thigh muscle attenuation was associated with 15 m decrease in 6MWD (95% CI -21 to -10). CT imaging may improve candidate risk stratification.

Indexed as

AdiposityLung TransplantationAbdominal WallAgedCohort StudiesFemaleHumansLung DiseasesMaleMiddle AgedMuscle, SkeletalRisk AssessmentSurvival RateThighTomography, X-Ray ComputedTreatment Outcomeclinical epidemiologyimaging/CT MRI etclung transplantation

Identifiers

PMID32482837
PMCPMC7888552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.