Evidence map›Paper›PMID 32482756›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2020

OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP.

Yuchen Zhang, Melissa Ruggiero, Bruno Hagenbuch

Open access · bronzeAbstract read
In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. AssessingPharmaceutics · 2023
    Article
  6. Article
  7. Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane.Drug metabolism and disposition: the biological fate of chemicals · 2023
    Article
  8. Free Cholesterol Affects the Function and Localization of Human NaInternational journal of molecular sciences · 2022
    Article
  9. Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.Drug metabolism and disposition: the biological fate of chemicals · 2022
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yuchen ZhangDepartment of Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas.
Melissa RuggieroDepartment of Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas.
Bruno HagenbuchDepartment of Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas bhagenbuch@kumc.edu.ORCID 0000-0002-2938-8630
University of Kansas Medical Center · US

Funding

Nuclear Receptors in Liver Health and DiseaseP20GM103549 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI JAESCHKE, HARTMUT W. · 2012 to 2015
$8.1M
Pilot Grants ProgramP30GM118247 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI WEINMAN, STEVEN A · 2016 to 2020
$5.5M
Molecular Characterization of Hepatic Organic Anion Transporting PolypeptidesR01GM077336 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI HAGENBUCH, BRUNO · 2007 to 2019
$3.7M
NIGMS NIH HHS P20 GM103549NIGMS NIH HHS P30 GM118247NIGMS NIH HHS R01 GM077336
6 · The paper itself

Abstract

Organic anion transporting polypeptide (OATP) 1B3 is a drug transporter expressed at the basolateral membrane of human hepatocytes. Along with other transporters, including OATP1B1, Na

Indexed as

AdultCells, CulturedChildGene Expression RegulationHEK293 CellsHepatocytesHumansLiver-Specific Organic Anion Transporter 1MaleOrganic Anion Transporters, Sodium-DependentOrganic Cation Transporter 1Primary Cell CultureProtein MultimerizationSincalideSolute Carrier Organic Anion Transporter Family Member 1B3SymportersLiver-Specific Organic Anion Transporter 1Organic Anion Transporters, Sodium-DependentOrganic Cation Transporter 1SincalideSLCO1B1 protein, humanSLCO1B3 protein, humansodium-bile acid cotransporterSolute Carrier Organic Anion Transporter Family Member 1B3Symporters

Identifiers

PMID32482756
PMCPMC7370998
OpenAlexW3031379342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.