Evidence map›Paper›PMID 32482677›Full record

ArticleAntimicrobial agents and chemotherapy2020

Fitness Cost and Compensatory Evolution in Levofloxacin-Resistant

Rui Pi, Qingyun Liu, Howard E Takiff, Qian Gao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Large-Scale Analysis of Fitness Cost ofFrontiers in cellular and infection microbiology · 2022
    Article
  4. Frontiers in microbiology · 2022
    Article
  5. The evolving biology ofFrontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Rui PiKey Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Shanghai Public Health Clinical Center Fudan University, Shanghai, China.
Qingyun LiuKey Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Shanghai Public Health Clinical Center Fudan University, Shanghai, China.
Howard E TakiffIntegrated Mycobacterial Pathogenomics Unit, Institut Pasteur, Paris, France.
Qian GaoKey Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Shanghai Public Health Clinical Center Fudan University, Shanghai, China qiangao@fudan.edu.cn.ORCID 0000-0002-8489-3672
Shanghai Public Health Clinical Center · CNInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We isolated spontaneous levofloxacin-resistant strains of

Indexed as

Mycobacterium tuberculosisDrug Resistance, BacterialLevofloxacinMutationMycobacteriaceaeLevofloxacincompensatory mutationfitness costlevofloxacinmycobacteriaresistance

Identifiers

PMID32482677
PMCPMC7526816
OpenAlexW3031323543

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.