Evidence map›Paper›PMID 32482642›Full record

ArticleInfection and immunity2020

Legionella pneumophila Excludes Autophagy Adaptors from the Ubiquitin-Labeled Vacuole in Which It Resides.

Titilayo O Omotade, Craig R Roy

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. mBio · 2026
    Article
  4. Article
  5. Review
  6. A diverse family of bacterial deubiquitinases is defined by theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Cryo-EM structure revealed a novel F-actin binding motif in abioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Autophagy and Bacterial infections.Autophagy reports · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Breaking the cellular defense: the role of autophagy evasion inFrontiers in cellular and infection microbiology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Eat or Be Eaten: Strategies Used byInfection and immunity · 2023
    Review
  19. CLEC12A Binds toInternational journal of molecular sciences · 2023
    Article
  20. ReplicativebioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Titilayo O OmotadeDepartment of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, New Haven, Connecticut, USA.
Craig R RoyDepartment of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, New Haven, Connecticut, USA craig.roy@yale.edu.ORCID 0000-0003-4490-440X
Yale University · US

Funding

Genetic Analysis of Legionella Phagosome TraffickingR37AI041699 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2012 to 2021
$5.3M
PREDOCTORAL TRAINING PROGRAM IN MICROBIAL PATHOGENESIST32AI007640 · NIAID · YALE UNIVERSITY · PI GOODMAN, ANDREW L · 2000 to 2022
$4.3M
NIAID NIH HHS R37 AI041699NIAID NIH HHS T32 AI007640
6 · The paper itself

Abstract

Xenophagy targets intracellular pathogens for destruction by the host autophagy pathway. Ubiquitin chains are conjugated to xenophagic targets and recruit multiple autophagy adaptors. The intracellular pathogen

Indexed as

AnimalsAutophagyBacterial ProteinsCHO CellsCricetulusGene Expression RegulationHost-Pathogen InteractionsHumansLegionella pneumophilaListeria monocytogenesMacrophagesMiceSequestosome-1 ProteinStaining and LabelingType IV Secretion SystemsUbiquitinBacterial ProteinsSequestosome-1 ProteinSqstm1 protein, mouseType IV Secretion SystemsUbiquitinautophagybacterial effector proteinsLegionella pneumophilatype IV secretion

Identifiers

PMID32482642
PMCPMC7375760
OpenAlexW3032044263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.