Evidence map›Paper›PMID 32482587›Full record

ArticleResearch in social & administrative pharmacy : RSAP2021

Time-trend analysis of medicine sales and shortages during COVID-19 outbreak: Data from community pharmacies.

Sónia Romano, Heloísa Galante, Débora Figueira, Zilda Mendes, António Teixeira Rodrigues

Abstract read
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Article in Research in social & administrative pharmacy : RSAP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

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0cells of the map it votes in
35citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Primary health care research & development · 2026
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  3. Article
  4. Review
  5. Article
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  7. Article
  8. Article
  9. Exploring Drug Shortages in the United Kingdom.Pharmacy (Basel, Switzerland) · 2023
    Article
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  11. Article
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  13. Review
  14. Article
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  16. A better normal in Canada will need a better detection system for emerging and re-emerging respiratory pathogens.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Article
  17. Article
  18. Article
  19. COVID-19 Medical and Pharmacological Management in the European Countries Compared to Italy: An Overview.International journal of environmental research and public health · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sónia RomanoCentre for Health Evaluation & Research/Infosaúde, National Association of Pharmacies (CEFAR/IS-ANF), Rua Marechal Saldanha 1, 1249-069, Lisbon, Portugal. Electronic address: sonia.romano@anf.pt.
Heloísa GalanteCentre for Health Evaluation & Research/Infosaúde, National Association of Pharmacies (CEFAR/IS-ANF), Rua Marechal Saldanha 1, 1249-069, Lisbon, Portugal. Electronic address: heloisa.galante@anf.pt.
Débora FigueiraCentre for Health Evaluation & Research/Infosaúde, National Association of Pharmacies (CEFAR/IS-ANF), Rua Marechal Saldanha 1, 1249-069, Lisbon, Portugal. Electronic address: debora.figueira@anf.pt.
Zilda MendesCentre for Health Evaluation & Research/Infosaúde, National Association of Pharmacies (CEFAR/IS-ANF), Rua Marechal Saldanha 1, 1249-069, Lisbon, Portugal. Electronic address: zilda.mendes@anf.pt.
António Teixeira RodriguesCentre for Health Evaluation & Research/Infosaúde, National Association of Pharmacies (CEFAR/IS-ANF), Rua Marechal Saldanha 1, 1249-069, Lisbon, Portugal. Electronic address: antoniot.rodrigues@anf.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 is a worldwide public health concern. Disruptions in the drug market are expected and shortages might worsen. Community pharmacies can contribute to early identification and report of medicines' supply and demand issues.

objectiveThe aim of this study is to characterize the impact of the COVID-19 outbreak on outpatient medicines' sales and shortages.

methodsA retrospective, time-trend analysis of medicine sales, shortages and laboratory-confirmed COVID-19 cases was performed from February 1st to April 30th, 2020, and its homologous period (regarding sales only). A detailed analysis of 6 pharmaceutical substances was performed. All data were subjected to rescaling using the min-max normalization method, in order to become comparable. Data analysis was performed using Microsoft® Excel.

resultsThe pandemic resulted in an increase in medicines' demand and reported shortages during the early stage of the outbreak. The maximum proportion of medicine sales was registered on March 13th, 2020, 4 days after the WHO declared COVID-19 a pandemic. By the end of March, sales have already dropped to proportions similar to those of 2019. The maximum proportion of drug shortages was reached about one week after the sales peak and by the end of the study period were below those recorded in the pre-COVID-19 period. The analyzed drugs were paracetamol, ascorbic acid, dapagliflozin plus metformin, rosuvastatin plus ezetimibe, formoterol, and hydroxychloroquine, as these pharmaceutical substances registered the highest growth rate in sales and shortages when compared to the same period in the previous year. Hydroxychloroquine showed the most different pattern trends on sales and shortages of these medicines.

conclusionsPharmacies can provide timely and real-world data regarding sales and shortages. The adopted measures to guarantee the continuous supply of the medicine market seem to have worked. The long-term impacts of this pandemic are unknown and should continue to be closely monitored.

Indexed as

COVID-19CommerceCommunity Pharmacy ServicesDisease OutbreaksHumansPharmaceutical PreparationsRetrospective StudiesTime FactorsPharmaceutical PreparationsCOVID-19DemandMedicinePharmaciesShortages

Identifiers

PMID32482587
PMCPMC7245321

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.