Evidence map›Paper›PMID 32482364›Full record

ArticleAtencion primaria2020

Long-term impact of an intervention on rapid antigen detection tests in acute pharyngitis.

José M Molero, Gloria Cordoba, Beatriz González López-Valcárcel, Ana Moragas, Juan E Losa, Carles Llor

Open access · goldAbstract read
In one paragraph

Article in Atencion primaria, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

José M MoleroSan Andrés Health Centre, Department Preventive Medical Specialties and Public Health, University Rey Juan Carlos, Madrid, Spain.
Gloria CordobaSection of General Practice and Research Unit for General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Beatriz González López-ValcárcelDepartment of Quantitative Methods for Economics and Management, University of Las Palmas, Las Palmas de Gran Canaria, Canary Islands, Spain.
Ana MoragasUniversity Rovira i Virgili, Jaume I Health Centre, Tarragona, Catalonia, Spain.
Juan E LosaDepartment of Health Sciences II-Facultad de Ciencias de la Salud, University Juan Carlos, Hospital Universitario Fundación Alarcón, Madrid, Spain.
Carles LlorSection of General Practice and Research Unit for General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark; University Institute in Primary Care Research Jordi Gol, Via Roma Health Centre, Barcelona, Spain. Electronic address: carles.llor@gmail.com.
Institut Universitari d'Investigació en Atenció Primària Jordi Gol · ESUniversidad de Las Palmas de Gran Canaria · ESUniversidad Rey Juan Carlos · ESUniversidad Rovira i Virgili · ESUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was aimed at evaluating the appropriateness of use and interpretation of rapid antigen detection testing (RADT) and antibiotic prescribing for acute pharyngitis six years after a multifaceted intervention.

designBefore-and-after audit-based study. LOCATION: Primary care centres in eight autonomous Communities.

participantsGeneral practitioners (GP) who had participated in the HAPPY AUDIT intervention study in 2008 and 2009 were invited to participate in a third audit-based study six years later (2015).

methodRADTs were provided to the participating practices and the GPs were requested to consecutively register all adults with acute pharyngitis. A registration form specifically designed for this study was used.

resultsA total of 121 GPs out of the 210 who participated in the first two audits agreed to participate in the third audit (57.6%). They registered 3394 episodes of pharyngitis in the three registrations. RADTs were used in 51.7% of all the cases immediately after the intervention, and in 49.4% six years later. Antibiotics were prescribed in 21.3% and 36.1%, respectively (P<.001), mainly when tonsillar exudates were present, and in 5.3% and 19.2% of those with negative RADT results (P<.001). On adjustment for covariables, compared to the antibiotic prescription observed just after the intervention, significantly more antibiotics were prescribed six years later (odds ratio: 2.24, 95% confidence interval: 1.73-2.89).

conclusionsThis study shows that that the long-term impact of a multifaceted intervention, focusing on the use and interpretation of RADT in patients with acute pharyngitis, is reducing.

Indexed as

General PractitionersPharyngitisStreptococcal InfectionsAdultAnti-Bacterial AgentsHumansPrimary Health CareStreptococcus pyogenesAnti-Bacterial AgentsAgentes antibacterianosAnti-bacterial agentsFaringitisIntervenciónInterventionPharyngitisPrueba antigénica rápidaRapid antigen detection test

Identifiers

PMID32482364
PMCPMC7713413
OpenAlexW3031394499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.