Evidence map›Paper›PMID 32481723›Full record

ReviewInternational journal of molecular sciences2020

Theragnostic Aspects and Radioimmunotherapy in Pediatric Tumors.

Andrea Cimini, Maria Ricci, Agostino Chiaravalloti, Luca Filippi, Orazio Schillaci

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  8. [European journal of nuclear medicine and molecular imaging · 2023
    Article
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  10. Nuclear Medicine and Cancer Theragnostics: Basic Concepts.Diagnostics (Basel, Switzerland) · 2023
    Review
  11. [Diagnostics (Basel, Switzerland) · 2023
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  12. Head-to-Head Comparison between FDG andDiagnostics (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrea CiminiDepartment of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-0533-2947
Maria RicciDepartment of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-9277-6337
Agostino ChiaravallotiDepartment of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-8017-8858
Luca FilippiNuclear Medicine Section, "Santa Maria Goretti" Hospital, 04100 Latina, Italy.
Orazio SchillaciDepartment of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.
University of Rome Tor Vergata · ITOspedale Santa Maria Goretti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of theragnostic radiopharmaceuticals in nuclear medicine has grown rapidly over the years to combine the diagnosis and therapy of tumors. In this review, we performed web-based and desktop literature research to investigate and explain the potential role of theragnostic imaging in pediatric oncology. We focused primarily on patients with aggressive malignancies such as neuroblastoma and brain tumors, to select patients with the highest chance of benefit from personalized therapy. Moreover, the most critical and groundbreaking applications of radioimmunotherapy in children's oncology were examined in this peculiar context. Preliminary results showed the potential feasibility of theragnostic imaging and radioimmunotherapy in pediatric oncology. They revealed advantages in the management of the disease, thereby allowing an intra-personal approach and adding new weapons to conventional therapies.

Indexed as

RadioimmunotherapyAdolescentAnimalsBrain NeoplasmsChildChild, PreschoolHumansInternetNeuroblastomaNuclear MedicinePediatricsPositron-Emission TomographyPrecision MedicineRadiation OncologyRadiopharmaceuticalsSomatostatinRadiopharmaceuticalsSomatostatinneuroblastomanuclear medicinepediatric brain tumorspediatric tumorspersonalized therapypositron emission tomographyradioimmunotherapyradiopharmaceuticalssingle-photon emission computed tomographytheragnostics

Identifiers

PMID32481723
PMCPMC7312954
OpenAlexW3029609401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.