Evidence map›Paper›PMID 32481709›Full record

ArticleJournal of clinical medicine2020

Risk Stratification in Hypertrophic Cardiomyopathy. Insights from Genetic Analysis and Cardiopulmonary Exercise Testing.

Damiano Magrì, Vittoria Mastromarino, Giovanna Gallo, Elisabetta Zachara, Federica Re, Piergiuseppe Agostoni, Dario Giordano, Speranza Rubattu, Maurizio Forte, Maria Cotugno and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Contrasting the genetic architecture of cardiac glutathione against other organs: unveiling a unique tissue-specific locus.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 3 countries.

Damiano MagrìDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Vittoria MastromarinoDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Giovanna GalloDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.ORCID 0000-0003-4845-117X
Elisabetta ZacharaCardiac Arrhythmia Center and Cardiomyopathies Unit, San Camillo - Forlanini Hospital, 00100 Rome, Italy.
Federica ReCardiac Arrhythmia Center and Cardiomyopathies Unit, San Camillo - Forlanini Hospital, 00100 Rome, Italy.
Piergiuseppe AgostoniCentro Cardiologico Monzino, IRCCS, 20100 Milan, Italy.
Dario GiordanoDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Speranza RubattuDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Maurizio ForteIRCCS Neuromed, 86077 Pozzilli (IS), Italy.ORCID 0000-0003-0739-0534
Maria CotugnoIRCCS Neuromed, 86077 Pozzilli (IS), Italy.
Maria Rosaria TorrisiDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Simona PetrucciDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Aldo GermaniDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Camilla SavioUOC Medical Genetics and Advanced Cell Diagnostics, S. Andrea University Hospital, 00100 Rome, Italy.
Antonello MaruottiDepartment of Scienze Economiche, Politiche e Delle Lingue Moderne - Libera Università SS Maria Assunta, 00100 Rome, Italy.
Massimo VolpeDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Camillo AutoreDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Maria PianeDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
Beatrice MusumeciDepartment of Clinical and Molecular Medicine, Sapienza University, 00100 Rome, Italy.
CTO Andrea Alesini · ITSapienza University of Rome · ITIstituto Neurologico Mediterraneo · ITCarlo Forlanini Hospital · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITLibera Università Maria SS. Assunta · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of genetic testing over the clinical and functional variables, including data from the cardiopulmonary exercise test (CPET), in the hypertrophic cardiomyopathy (HCM) risk stratification remains unclear. A retrospective genotype-phenotype correlation was performed to analyze possible differences between patients with and without likely pathogenic/pathogenic (LP/P) variants. A total of 371 HCM patients were screened at least for the main sarcomeric genes

Indexed as

cardiopulmonary exercise testgenetic testinghypertrophic cardiomyopathy

Identifiers

PMID32481709
PMCPMC7356142
OpenAlexW3030824604

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.