Evidence map›Paper›PMID 32481682›Full record

ArticleMolecules (Basel, Switzerland)2020

Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[

Emad M Gad, Mohamed S Nafie, Elsayed H Eltamany, Magdy S A G Hammad, Assem Barakat, Ahmed T A Boraei

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 90 citations in OpenAlex.

  1. Cancer Chemopreventive Potential ofMolecules (Basel, Switzerland) · 2025
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  9. Synthesis,Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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  12. Design, synthesis, molecular modelling and antitumor evaluation ofJournal of enzyme inhibition and medicinal chemistry · 2023
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  14. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Novel 2-Sulfanylquinazolin-4(3Molecules (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Emad M GadChemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Mohamed S NafieChemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Elsayed H EltamanyChemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Magdy S A G HammadChemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Assem BarakatChemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Ahmed T A BoraeiChemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Suez Canal University · EGKing Saud University · SA

Funding

King Saud University RSP-2019/64
6 · The paper itself

Abstract

A multicomponent synthesis was empolyed for the synthesis of ethyl 2-amino-4,5,6,7-tetrahydrobenzo[

Indexed as

AlkylationAntineoplastic AgentsApoptosisBreast NeoplasmsCell Line, TumorCell ProliferationHep G2 CellsHumansMCF-7 CellsPyrimidinonesStructure-Activity RelationshipThiophenesAntineoplastic AgentsbenzothiophenePyrimidinonesThiophenesalkylationbenzo[b]thiopheneHepG-2JAK2 inhibitorMCF-7pyrimidinone

Identifiers

PMID32481682
PMCPMC7321303
OpenAlexW3028845553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.