Evidence map›Paper›PMID 32481675›Full record

ArticleInternational journal of molecular sciences2020

Development and Characterization of an Allergic Asthma Rat Model for Interventional Studies.

Marta Périz, Francisco J Pérez-Cano, Maria J Rodríguez-Lagunas, Trinitat Cambras, Santiago Pastor-Soplin, Iván Best, Margarida Castell, Malén Massot-Cladera

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Animals in Respiratory Research.International journal of molecular sciences · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Marta PérizSecció de Fisiologia, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), 08028 Barcelona, Spain.
Francisco J Pérez-CanoSecció de Fisiologia, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0001-6243-9164
Maria J Rodríguez-LagunasSecció de Fisiologia, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0001-7870-8250
Trinitat CambrasSecció de Fisiologia, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0002-9009-4690
Santiago Pastor-SoplinPrograma Cacao, Ingeniería Agroforestal, Facultad de Ciencias Ambientales, Universidad Científica del Sur, Lima 15842, Peru.
Iván BestPrograma Cacao, Ingeniería Agroforestal, Facultad de Ciencias Ambientales, Universidad Científica del Sur, Lima 15842, Peru.
Margarida CastellSecció de Fisiologia, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0001-5408-0593
Malén Massot-CladeraSecció de Fisiologia, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0002-5220-2793
Institute of Agrifood Research and Technology · ESUniversidad Científica del Sur · PEUniversitat de Barcelona · ES

Funding

Fondo Nacional de Desarrollo Científico, Tecnológico y de Innovación Tecnológica 137-2017-FONDECYT
6 · The paper itself

Abstract

Allergic asthma is one of the most common chronic diseases of the airways, however it still remains underdiagnosed and hence undertreated. Therefore, an allergic asthma rat model would be useful to be applied in future therapeutic strategy studies. The aim of the present study was to develop an objective model of allergic asthma in atopic rats that allows the induction and quantification of anaphylactic shock with quantitative variables. Female Brown Norway rats were intraperitoneally sensitized with ovalbumin (OVA), alum and

Indexed as

Disease Models, AnimalAdministration, IntranasalAllergensAnimalsAsthmaBody TemperatureBronchoalveolar Lavage FluidCytokinesEpithelial CellsFemaleHypersensitivityHypersensitivity, ImmediateImmunoglobulin ELeukotrienesLungOvalbuminAllergensCytokinesImmunoglobulin ELeukotrienesOvalbuminbody temperaturebronchoalveolar lavage fluidBrown Norway ratsIgEintranasal challengeleukotrienemotor activityovalbumin

Identifiers

PMID32481675
PMCPMC7312681
OpenAlexW3030976385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.