Evidence map›Paper›PMID 32481599›Full record

ArticleInternational journal of molecular sciences2020

Functional Expression of Piezo1 in Dorsal Root Ganglion (DRG) Neurons.

Jueun Roh, Sung-Min Hwang, Sun-Ho Lee, Kihwan Lee, Yong Ho Kim, Chul-Kyu Park

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 79 citations in OpenAlex.

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  13. Pharmacology of PIEZO1 channels.British journal of pharmacology · 2024
    Review
  14. Article
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  18. Piezo1: the key regulators in central nervous system diseases.Frontiers in cellular neuroscience · 2024
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jueun RohGachon Pain Center and Department of Physiology, College of Medicine, Gachon University, Incheon 21999, Korea.
Sung-Min HwangGachon Pain Center and Department of Physiology, College of Medicine, Gachon University, Incheon 21999, Korea.ORCID 0000-0003-2639-9761
Sun-Ho LeeDepartment of Neurosurgery, Spine tumor center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea.
Kihwan LeeGachon Pain Center and Department of Physiology, College of Medicine, Gachon University, Incheon 21999, Korea.
Yong Ho KimGachon Pain Center and Department of Physiology, College of Medicine, Gachon University, Incheon 21999, Korea.ORCID 0000-0001-8704-3553
Chul-Kyu ParkGachon Pain Center and Department of Physiology, College of Medicine, Gachon University, Incheon 21999, Korea.ORCID 0000-0002-4152-3022
Gachon University · KRSamsung Medical Center · KR

Funding

National Research Foundation of Korea NRF-2017M3C7A1025600National Research Foundation of Korea NRF-2018R1D1A1B07047849
6 · The paper itself

Abstract

Piezo channels are mechanosensitive ion channels. Piezo1 is primarily expressed in nonsensory tissues, whereas Piezo2 is predominantly found in sensory tissues, including dorsal root ganglion (DRG) neurons. However, a recent study demonstrated the intracellular calcium response to Yoda1, a selective Piezo1 agonist, in trigeminal ganglion (TG) neurons. Herein, we investigate the expression of

Indexed as

AnimalsCalciumCells, CulturedDependovirusFemaleGanglia, SpinalGene Expression RegulationHumansIon ChannelsMaleMechanotransduction, CellularMiceMice, Inbred C57BLPatch-Clamp TechniquesPyrazinesRNA, Small InterferingCalciumIon ChannelsPIEZO1 protein, humanPiezo1 protein, mousePyrazinesRNA, Small InterferingThiadiazolesTRPV1 protein, humanTRPV1 protein, mouseTRPV Cation Channelsyoda-1dorsal root ganglionmechanotransductionpainPiezoTRPV1

Identifiers

PMID32481599
PMCPMC7313462
OpenAlexW3030159217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.