Evidence map›Paper›PMID 32481589›Full record

ArticleInternational journal of molecular sciences2020

CSI NGS Portal: An Online Platform for Automated NGS Data Analysis and Sharing.

Omer An, Kar-Tong Tan, Ying Li, Jia Li, Chan-Shuo Wu, Bin Zhang, Leilei Chen, Henry Yang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

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  12. Resources and tools for rare disease variant interpretation.Frontiers in molecular biosciences · 2023
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  14. Genome research · 2022
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  16. Chronic Benzene Exposure Aggravates Pressure Overload-Induced Cardiac Dysfunction.Toxicological sciences : an official journal of the Society of Toxicology · 2021
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Omer AnCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0002-5762-6253
Kar-Tong TanCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Ying LiCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Jia LiCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Chan-Shuo WuCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Bin ZhangCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Leilei ChenCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Henry YangCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
National University of Singapore · SG

Funding

Ministry of Education - Singapore MOE2014-T3-1-006National Research Foundation Singapore MOE2014-T3-1-006
6 · The paper itself

Abstract

Next-generation sequencing (NGS) has been a widely-used technology in biomedical research for understanding the role of molecular genetics of cells in health and disease. A variety of computational tools have been developed to analyse the vastly growing NGS data, which often require bioinformatics skills, tedious work and a significant amount of time. To facilitate data processing steps minding the gap between biologists and bioinformaticians, we developed CSI NGS Portal, an online platform which gathers established bioinformatics pipelines to provide fully automated NGS data analysis and sharing in a user-friendly website. The portal currently provides 16 standard pipelines for analysing data from DNA, RNA, smallRNA, ChIP, RIP, 4C, SHAPE, circRNA, eCLIP, Bisulfite and scRNA sequencing, and is flexible to expand with new pipelines. The users can upload raw data in FASTQ format and submit jobs in a few clicks, and the results will be self-accessible via the portal to view/download/share in real-time. The output can be readily used as the final report or as input for other tools depending on the pipeline. Overall, CSI NGS Portal helps researchers rapidly analyse their NGS data and share results with colleagues without the aid of a bioinformatician. The portal is freely available at: https://csibioinfo.nus.edu.sg/csingsportal.

Indexed as

AutomationComputational BiologyData AnalysisElectronic Data ProcessingHigh-Throughput Nucleotide SequencingHumansInternetProgramming LanguagesRNA-SeqRNA, Small NucleolarSignal Processing, Computer-AssistedSoftwareUser-Computer InterfaceRNA, Small Nucleolarbioinformatics pipelinesNGS data analysisNGS pipelines

Identifiers

PMID32481589
PMCPMC7312552
OpenAlexW2979791414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.