Evidence map›Paper›PMID 32481533›Full record

ReviewCancers2020

FDG-PET/CT, a Promising Exam for Detecting High-Risk Myeloma Patients?

Anne-Victoire Michaud-Robert, Bastien Jamet, Clément Bailly, Thomas Carlier, Philippe Moreau, Cyrille Touzeau, Mickael Bourgeois, Françoise Kraeber-Bodere, Caroline Bodet-Milin

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. New Developments in Myeloma Treatment and Response Assessment.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  3. Article
  4. Review
  5. Molecular Signature ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anne-Victoire Michaud-RobertNuclear Medicine Department, Nantes University Hospital, 44093 Nantes, France.
Bastien JametNuclear Medicine Department, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0002-2145-9182
Clément BaillyNuclear Medicine Department, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0001-8313-3287
Thomas CarlierNuclear Medicine Department, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0002-6932-7322
Philippe MoreauCRCINA, INSERM, CNRS, Angers University, Nantes University, 44093 Nantes, France.
Cyrille TouzeauCRCINA, INSERM, CNRS, Angers University, Nantes University, 44093 Nantes, France.ORCID 0000-0003-0275-2575
Mickael BourgeoisNuclear Medicine Department, Nantes University Hospital, 44093 Nantes, France.
Françoise Kraeber-BodereNuclear Medicine Department, Nantes University Hospital, 44093 Nantes, France.
Caroline Bodet-MilinNuclear Medicine Department, Nantes University Hospital, 44093 Nantes, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is a haematological neoplasm characterized by a clonal proliferation of malignant plasma cells in the bone marrow. MM is associated with high morbidity and mortality and variable survival, which can be very short for some patients but over 10 years for others. These differences in survival are explained by intra- and inter-tumoral heterogeneity and demonstrate the potential benefits of adapting the treatment course for high-risk patients with a poorer prognosis. Indeed, identification of these high-risk patients is necessary and is based on the identification of high-risk biomarkers including clinical variables, genomics and imaging results. Positron emission tomography combined with computed tomography using 18F-deoxyfluoroglucose (FDG-PET/CT) is a reliable technique for the initial staging of patients with symptomatic multiple myeloma (MM), and has been included in the IMWG (International Myeloma Working Group) recommendations in 2019. According to clinical studies, FDG-PET/CT characteristics could be used to define high-risk patients at initial diagnosis of symptomatic MM. The goal of this review is to demonstrate the prognostic value of FDG-PET in symptomatic MM patients, particularly in identifying high-risk patients, and thus, to best adapt therapeutic management in the future.

Indexed as

FDG-PET/CThigh-risk patientsmultiple myelomaprognostic valuesmouldering multiple myeloma

Identifiers

PMID32481533
PMCPMC7352681
OpenAlexW3031258245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.