SynthesisInternational journal of molecular sciences2020
Reference Ranges of 8-Isoprostane Concentrations in Exhaled Breath Condensate (EBC): A Systematic Review and Meta-Analysis.
Synthesis in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Isoprostanes in wastewater of two Italian cities as a community-level metabolism linked to SARS-CoV-2 RNA and COVID-19 cases.BMC public health · 2025Article
- Preventive effect of precautionary lowered exposure or adaptation of nanomaterial workers?Central European journal of public health · 2025Article
- Uncovering the efficacy of a natural homemade sunscreen in protection from ultraviolet radiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Impacts of vaping and marijuana use on airway health as determined by exhaled breath condensate (EBC).Respiratory research · 2025Article
- Exhaled Breath Analysis: From Laboratory Test to Wearable Sensing.IEEE reviews in biomedical engineering · 2025Review
- The Role of Exhaled Breath Condensate in Chronic Inflammatory and Neoplastic Diseases of the Respiratory Tract.International journal of molecular sciences · 2024Review
- Discriminative potential of exhaled breath condensate biomarkers with respect to chronic obstructive pulmonary disease.Journal of occupational medicine and toxicology (London, England) · 2024Article
- Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infants.BMC pediatrics · 2023Article
- Oxidative Stress and Inflammatory Biomarkers for Populations with Occupational Exposure to Nanomaterials: A Systematic Review and Meta-Analysis.Antioxidants (Basel, Switzerland) · 2022Review
- Pathophysiological Concepts and Management of Pulmonary Manifestation of Pediatric Inflammatory Bowel Disease.International journal of molecular sciences · 2022Review
- Review
- Challenges in Quantifying 8-OHdG and 8-Isoprostane in Exhaled Breath Condensate.Antioxidants (Basel, Switzerland) · 2022Article
- A Biomonitoring Pilot Study in Workers from a Paints Production Plant Exposed to Pigment-Grade Titanium Dioxide (TiOToxics · 2022Article
- A pilot study of total personal exposure to volatile organic compounds among Hispanic female domestic cleaners.Journal of occupational and environmental hygiene · 2022Article
- Respiratory Disease Occupational Biomonitoring Collaborative Project (ROBoCoP): A longitudinal pilot study and implementation research in the Parisian transport company.Journal of occupational medicine and toxicology (London, England) · 2021Article
- Three-Year Study of Markers of Oxidative Stress in Exhaled Breath Condensate in Workers Producing Nanocomposites, Extended by Plasma and Urine Analysis in Last Two Years.Nanomaterials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Isoprostanes are physiopathologic mediators of oxidative stress, resulting in lipid peroxidation. 8-isoprostane seems particularly useful for measuring oxidative stress damage. However, no reference range values are available for 8-isoprosante in exhaled breath condensate (EBC) of healthy adults, enabling its meaningful interpretation as a biomarker. We conducted this systematic review and meta-analysis according to the protocol following PROSPERO (CRD42020146623). After searching and analyzing the literature, we included 86 studies. After their qualitative synthesis and risk of bias assessment, 52 studies were included in meta-analysis. The latter focused on studies using immunological analytical methods and investigated how the concentrations of 8-isoprostane differ based on gender. We found that gender had no significant effect in 8-isoprostane concentration. Among other studied factors, such as individual characteristics and factors related to EBC collection, only the device used for EBC collection significantly affected measured 8-isoprostane concentrations. However, adjustment for the factors related to EBC collection, yielded uncertainty whether this effect is due to the device itself or to the other factors. Given this uncertainty, we estimated the reference range values of 8-isoprostane stratified by gender and EBC collection device. A better standardization of EBC collection seems necessary; as well more studies using chemical analytical methods to extend this investigation.
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