Evidence map›Paper›PMID 32481417›Full record

ArticleMedicine2020

Transforaminal debridement with a posterior-only approach involving placement of an interbody bone graft combined with diseased vertebral fixation for the treatment of thoracic and lumbar tuberculosis: Minimum 5-year follow-up.

Chen Zhao, Lei Luo, Xiaobing Pu, Liehua Liu, Pei Li, Lichuan Liang, Fei Luo, Tianyong Hou, Fei Dai, Jianzhong Xu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Chen ZhaoDepartment of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing.
Lei LuoDepartment of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing.
Xiaobing PuDepartment of Orthopedic Surgery, No. 4 West China Teaching Hospital, Sichuan University, Chengdu, Sichuan.
Liehua LiuGraduate School, Ningxia Medical University, Yinchuan, Ningxia.
Pei LiDepartment of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing.
Lichuan LiangDepartment of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing.
Fei LuoDepartment of Orthopedics, Southwest Hospital, The Army (Third Military) Medical University, Chongqing, China.
Tianyong HouDepartment of Orthopedics, Southwest Hospital, The Army (Third Military) Medical University, Chongqing, China.
Fei DaiDepartment of Orthopedics, Southwest Hospital, The Army (Third Military) Medical University, Chongqing, China.
Jianzhong XuDepartment of Orthopedics, Southwest Hospital, The Army (Third Military) Medical University, Chongqing, China.
Qiang ZhouDepartment of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing.
Chongqing Medical University · CNSouthwest Hospital · CNNingxia Medical University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the clinical and imaging results of transforaminal debridement with a posterior-only approach involving placement of an interbody bone graft combined with diseased vertebral fixation for the treatment of thoracic and lumbar tuberculosis (TB) with a minimum 5-year follow-up.Sixty-five patients who presented with active thoracic and lumbar TB between October 2006 and August 2013 were retrospectively analyzed: 20 were thoracic TB (group A), 17 were thoracolumbar TB (group B), and 28 were lumbar TB (group C). The patient data, operating time, blood loss, Visual Analog Scale score, Oswestry Disability Index score, correction of kyphosis, recovery of neurological function, and complications were recorded and analyzed.The patients were followed for 68.7 ± 17.8 months. The preoperative average Cobb angles of kyphosis in patients in groups A, B, and C significantly decreased from 28.2 ± 11.9°, 30.5 ± 16.9°, and 10.9 ± 8.8° before surgery to 8.0 ± 5.4°, 5.0 ± 4.1°, and -4.4 ± 1.6° (- indicates lordosis) after surgery, respectively. At the final follow-up time, the Cobb angles were 9.2 ± 6.1°, 6.8 ± 10.0°, and -3.7 ± 2.0°, respectively. The postoperative Cobb angles of kyphosis were significantly improved in all groups (P < .05). The correction loss angles were larger in groups A and B than in group C (P > .05). The operating time, blood loss, and complications were not significantly different between the groups (P > .05). Three (4.6%) patients developed unhealed TB during postoperative anti-TB treatment, and 6 patients (9.2%) with TB relapsed after healing from surgery.The posterior-only approach for the surgical treatment of thoracic and lumbar TB achieved satisfactory outcomes over long-term follow-up. The implantation of pedicle screws in diseased vertebrae reduced the range of fixation, but patients with thoracic and thoracolumbar TB should undergo fixation to at least 1 adjacent normal segment. There were some cases of recurrence after TB healed, and long-term follow-up is therefore necessary.

Indexed as

AdultBone TransplantationDebridementFemaleFollow-Up StudiesHumansLumbar VertebraeMaleRetrospective StudiesSpinal FusionThoracic VertebraeTreatment OutcomeTuberculosis, Spinal

Identifiers

PMID32481417
PMCPMC12245233
OpenAlexW3030288515

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.