Evidence map›Paper›PMID 32481311›Full record

ArticleMedicine2020

Effect of grelin on TRX expression in chronic heart failure tissue: A protocol of systematic review and meta-analysis.

Zhe Chen, Yao Feng, Ru-Bing Zhang, Xin Li, Jian-Bo Xu

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Zhe ChenDepartment of Critical Medicine.
Yao FengDepartment of Acupuncture and Moxibustion.
Ru-Bing ZhangThird Ward of Cardiology Department, First Affiliated Hospital of Jiamusi University.
Xin LiDepartment of General Medicine, Jiamusi Central Hospital, Jiamusi, China.
Jian-Bo XuDepartment of Critical Medicine.ORCID 0000-0002-8401-2185
International Data Group (Sweden) · SEFirst Affiliated Hospital of Jiamusi University · CNJiamusi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study is to explore the effect of grelin on TRX expression (TRXE) in chronic heart failure tissue (CHFT).

methodsWe will search electronic databases from inception to the March 1, 2020 in MEDLINE, EMBASE, Cochrane Library, CINAHL, PEDro, the Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. We will not apply any limitations to the language and publication status. Any randomized controlled trials (RCTs) that studied the effect of grelin on TRXE in CHFT will be included. Study quality will be checked by Cochrane risk of bias and evidence quality will be appraised by Grading of Recommendations Assessment Development and Evaluation. All extracted data will be analyzed by RevMan 5.3 Software.

resultsThis study will summarize the present RCTs to assess the effect of grelin on TRXE in CHFT.

conclusionThe results of this study will provide conclusive evidence of the effect of grelin on TRXE in CHFT. SYSTEMATIC REVIEW REGISTRATION: INPLASY202040078.

Indexed as

DNADrugs, Chinese HerbalGene Expression RegulationHeart FailureHumansMedicine, Chinese TraditionalMeta-Analysis as TopicSystematic Reviews as TopicThioredoxinsDNADrugs, Chinese HerbalThioredoxinsTXN protein, human

Identifiers

PMID32481311
PMCPMC7249932
OpenAlexW3016625947

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.