Evidence map›Paper›PMID 32481287›Full record

Trial reportMedicine2020

Clinical observation of Dan-Hong Hua-Yu oral solution in treating retinal vein occlusion.

Tie-Jun Li, Yu-Chen Sun, Qiu-Yan Ma, Yan Wu, Chao Yang, Nan Zhang, Yue Yang, Ying-Xin Yang

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05814640 (Sequenced Treatment Alternatives to Relieve Adolescent Depression), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05814640 phase1 / phase2recruitingnot on this mapstarted 2023, after this paper: background citation

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD): a Pragmatic Clinical Trial

TypeinterventionalSponsorFirst Affiliated Hospital of Chongqing Medical UniversityRan2023 to 2027Enrolled520ConditionsDepression, SequestraArmsFluoxetine, Sertraline, Vortioxetine, Duloxetine, Aripiprazole
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tie-Jun LiBeijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Yu-Chen SunDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Qiu-Yan MaBeijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Yan WuBeijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Chao YangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Nan ZhangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Yue YangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University.
Ying-Xin YangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University.ORCID 0000-0002-1338-1418
Capital Medical University · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRetinal vein occlusion refers to diseases with decreased vision, dilated tortuous retinal veins visible on the fundus, and retinal hemorrhage, edema, and osmosis distributed along the vein. There is still no ideal intervention to treat central retinal vein occlusion. This study plan to observe the efficacy of Dan-Hong Hua-Yu oral solution in treating non-ischemic retinal vein occlusion, in order to provide new treatment ideas. METHODS/

designWe plan to use random number table method, 64 cases of non-ischemic central retinal vein occlusion that meet the inclusion criteria will be randomly divided into a treatment group and a control group. The intervention group will be treated with Dan-Hong Hua-Yu oral solution according to the syndrome differentiation of Traditional Chinese medicine and the patient's fundus condition. Each group will take 4 weeks as a course of treatment and three consecutive courses of treatment without any interval during the course of treatment. Changes of visual acuity, fundus performance, and total clinical symptoms of patients before and after treatment will be observed. DISCUSSION: This study will observe the efficacy of Dan-Hong Hua-Yu oral solution in the treatment of non-ischemic central retinal vein occlusion, with a view to providing new treatment ideas.

trial registrationClinicalTrials.gov, ChiCTR2000030625, Registered on March 08, 2020.

Indexed as

Administration, OralAdultAgedCase-Control StudiesChinaDrugs, Chinese HerbalFemaleFluorescein AngiographyFundus OculiHumansMacular EdemaMaleMiddle AgedRetinal Vein OcclusionVisual Acuitydanhong huayu koufuyeDrugs, Chinese Herbal

Identifiers

PMID32481287
PMCPMC7249849
OpenAlexW3031793034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.