Evidence map›Paper›PMID 32479601›Full record

ArticleNucleic acids research2020

CReSCENT: CanceR Single Cell ExpressioN Toolkit.

Suluxan Mohanraj, J Javier Díaz-Mejía, Martin D Pham, Hillary Elrick, Mia Husić, Shaikh Rashid, Ping Luo, Prabnur Bal, Kevin Lu, Samarth Patel and 9 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Suluxan MohanrajPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 0A3, Canada.
J Javier Díaz-MejíaPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 0A3, Canada.
Martin D PhamCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Hillary ElrickCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Mia HusićCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Shaikh RashidCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Ping LuoPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 0A3, Canada.
Prabnur BalCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Kevin LuCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Samarth PatelCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Alaina MahalanabisCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Alaine NaidasUniversity of Western Ontario, London, ON N6A 3K7, Canada.
Erik ChristensenUniversity of Western Ontario, London, ON N6A 3K7, Canada.
Danielle CroucherPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 0A3, Canada.
Laura M RichardsPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 0A3, Canada.
Parisa ShooshtariUniversity of Western Ontario, London, ON N6A 3K7, Canada.
Michael BrudnoCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Arun K RamaniCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Trevor J PughPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 0A3, Canada.
Hospital for Sick Children · CAUniversity Health Network · CAOntario Institute for Cancer Research · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CReSCENT: CanceR Single Cell ExpressioN Toolkit (https://crescent.cloud), is an intuitive and scalable web portal incorporating a containerized pipeline execution engine for standardized analysis of single-cell RNA sequencing (scRNA-seq) data. While scRNA-seq data for tumour specimens are readily generated, subsequent analysis requires high-performance computing infrastructure and user expertise to build analysis pipelines and tailor interpretation for cancer biology. CReSCENT uses public data sets and preconfigured pipelines that are accessible to computational biology non-experts and are user-editable to allow optimization, comparison, and reanalysis for specific experiments. Users can also upload their own scRNA-seq data for analysis and results can be kept private or shared with other users.

Indexed as

SoftwareHumansNeoplasmsRNA-SeqSingle-Cell AnalysisT-Lymphocytes

Identifiers

PMID32479601
PMCPMC7319570
OpenAlexW3028851061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.