Evidence map›Paper›PMID 32479548›Full record

Observational studyPloS one2020

Determinants of motor, language, cognitive, and global developmental delay in children with complicated severe acute malnutrition at the time of discharge: An observational study from Central India.

Navneet Khandelwal, Jagdish Mandliya, Kamna Nigam, Vandana Patil, Aditya Mathur, Ashish Pathak

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Navneet KhandelwalDepartment of Pediatrics, AIIMS, Bhopal, India.ORCID 0000-0003-0581-5260
Jagdish MandliyaDepartment of Pediatrics, R. D. Gardi Medical College, Ujjain, India.
Kamna NigamDepartment of Pediatrics, R. D. Gardi Medical College, Ujjain, India.ORCID 0000-0002-9281-1366
Vandana PatilDepartment of Pediatrics, R. D. Gardi Medical College, Ujjain, India.ORCID 0000-0001-5419-7070
Aditya MathurDepartment of Pediatrics, R. D. Gardi Medical College, Ujjain, India.ORCID 0000-0003-2404-9231
Ashish PathakDepartment of Pediatrics, R. D. Gardi Medical College, Ujjain, India.ORCID 0000-0002-7576-895X
Ruxmaniben Deepchand Gardi Medical College · INAll India Institute of Medical Sciences Bhopal · INUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUndernutrition leads to impaired psychosocial and cognitive development. This study explored the developmental status of children with complicated severe acute malnutrition (SAM) and correlated it with various risk factors for SAM. METHODS AND

findingsWe recruited 100 children with SAM and no other associated significant health issues during the recovery phase of treatment using the Bayley Scales of Infant and Toddler Development III prior to discharge from the nutritional rehabilitation unit in R D Gardi Medical College, Ujjain, Central India. We also assessed composite developmental scores, developmental age equivalents, and average differences in developmental age. Risk factors for developmental delay were identified in children with complicated SAM. The results revealed that 75%, 75%, and 63% of children with SAM exhibited delay in motor (mean score: 78.22), language (mean score: 83.97), and cognitive (mean score: 78.06) domains, respectively. A total of 63% children exhibited delay by an average of 4-7 months in the total developmental age. The proportion of children with delay in motor, language, and cognitive domains was determined. An increased risk of global developmental delay was observedin children with a low birth weight (adjusted odds ratio [aOR]: 18.06, 95%CI: 2.08-156.56; P = 0.009), having working mothers (aOR: 17.54, 95%CI: 3.02-102.59; P = 0.001), weight-for-age less than three standard deviations (aOR: 6.09, 95%CI: 1.08-34.10; P = 0.04), and presence of severe anemia (aOR: 16.34, 95%CI: 2.94-90.73; P = 0.001).

conclusionsThe results indicated that children with SAM exhibit developmental delay across all domains. Identifying multiple modifiable risk factors for developmental delay in children with SAM will be helpful in devising early interventional strategies in low-middle income countries; however, the exact timing of such interventions should be investigated.

Indexed as

Child DevelopmentChild, PreschoolCross-Sectional StudiesDevelopmental DisabilitiesFeeding BehaviorFemaleHumansIndiaInfantLanguageMalePatient DischargeRisk FactorsSevere Acute Malnutrition

Identifiers

PMID32479548
PMCPMC7263621
OpenAlexW3030005691

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.