Evidence map›Paper›PMID 32479502›Full record

ArticlePloS one2020

A Delphi consensus on the management of oral anticoagulation in patients with non-valvular atrial fibrillation in Spain: ACOPREFERENCE study.

Carlos Escobar, Xavier Borrás, Ramón Bover Freire, Carlos González-Juanatey, Miren Morillas, Alfonso Valle Muñoz, Juan José Gómez-Doblas

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  9. Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: A Position Paper from the ESC Working Group on Thrombosis, in collaboration with the European Heart Rhythm Association, the Association for Acute CardioVascular Care and the Asia-Pacific Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Carlos EscobarCardiology Department, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0001-5584-4735
Xavier BorrásCardiology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Ramón Bover FreireCardiology Department, Hospital Clínico San Carlos, CIBERCV, Madrid, Spain.
Carlos González-JuanateyCardiology Department, Hospital Universitario Lucus Augusti, Lugo, Spain.
Miren MorillasCardiology Department, Hospital de Galdakao, Galdakao, Bizkaia, Spain.
Alfonso Valle MuñozCardiology Department, Hospital Marina Salud, Denia, Alicante, Spain.
Juan José Gómez-DoblasCardiology Department, Hospital Universitario Virgen de la Victoria, CIBERCV, Málaga, Spain.
Centro de Investigación en Red en Enfermedades Cardiovasculares · ESHospital Clínico San Carlos · ESHospital de Galdakao · ESHospital de Sant Pau · ESHospital Marina Baixa · ESHospital Universitario La Paz · ESHospital Universitario Lucus Augusti · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the level of agreement between cardiologists regarding the management of oral anticoagulation (OAC) in patients with non-valvular atrial fibrillation (NVAF) in Spain. MATERIALS AND

methodsA two-round Delphi study was performed using an online survey. In round 1, panel members rated their level of agreement with the questionnaire items on a 9-point Likert scale. Item selection was based on acceptance by ≥66.6% of panellists and the agreement of the scientific committee. In round 2, the same panellists evaluated those items that did not meet consensus in round 1.

resultsA total of 238 experts participated in round 1; of these, 217 completed the round 2 survey. In round 1, 111 items from 4 dimensions (Thromboembolic and bleeding risk evaluation for treatment decision-making: 18 items; Choice of OAC: 39 items; OAC in specific cardiology situations: 12 items; Patient participation and education: 42 items) were evaluated. Consensus was reached for 92 items (83%). Over 80% of the experts agreed with the use of DOACs as the initial anticoagulant treatment when OAC is indicated. Panellists recommended the use of DOACs in patients at high risk of thromboembolic complications (CHA2DS2-VASc ≥3) (83%), haemorrhages (HAS-BLED ≥3) (89%) and poor quality of anticoagulation control (SAMe-TT2R2 >2) (76%), patients who fail to achieve an optimal therapeutic range after 3 months on VKA treatment (93%), and those who are to undergo cardioversion (80%). Panellists agreed that the efficacy and safety profile of each DOAC (98%), the availability of a specific reversal agent (72%) and patient's preference (85%) should be considered when prescribing a DOAC. A total of 97 items were ultimately accepted after round 2.

conclusionsThis Delphi panel study provides expert-based recommendations that may offer guidance on clinical decision-making for the management of OAC in NVAF. The importance of patient education and involvement has been highlighted.

Indexed as

Administration, OralAdultAnticoagulantsAtrial FibrillationDelphi TechniqueFemaleHemorrhageHumansInternetMaleMiddle AgedPatient PreferencePhysiciansSpainSurveys and QuestionnairesThromboembolismAnticoagulants

Identifiers

PMID32479502
PMCPMC7263623
OpenAlexW3030516229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.