Evidence map›Paper›PMID 32479136›Full record

ArticleJournal of dental research2020

Childhood Oral Infections Associate with Adulthood Metabolic Syndrome: A Longitudinal Cohort Study.

P J Pussinen, S Paju, J Viikari, A Salminen, L Taittonen, T Laitinen, D Burgner, M Kähönen, T Lehtimäki, N Hutri-Kähönen and 2 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06286501 (Identification of Adolescent Patients at Risk of Oral Diseases and Targeting of Preventive Treatment, and the Use of Antibacterial Photodynamic Therapy as an Adjunctive Treatment Method), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06286501 narecruitingnot on this mapstarted 2024, after this paper: background citation

Identification of Adolescent Patients at Risk of Oral Diseases and Targeting of Preventive Treatment, and the Use of Antibacterial Photodynamic Therapy as an Adjunctive Treatment Method

TypeinterventionalSponsorWellbeing Services County of PirkanmaaRan2024 to 2025Enrolled120ConditionsDental Caries in Children, Dental Plaque, Tooth Decay, PeriodontitisArmsLumoral Treatment, Standard, personalized oral health care
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. [Oral Health Status of Obese Children andIntervention Strategies].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Systemic Metabolic Signatures of Oral Diseases.Journal of dental research · 2024
    Article
  14. Article
  15. Salivary Redox Homeostasis in Human Health and Disease.International journal of molecular sciences · 2022
    Review
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

P J PussinenOral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-3563-1876
S PajuOral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.
J ViikariDepartment of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
A SalminenOral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.
L TaittonenVaasa Central Hospital, Vaasa, Finland.
T LaitinenUniversity of Eastern Finland, Kuopio, Finland.
D BurgnerMurdoch Children's Research Institute, Royal Children's Hospital, Parkville, Australia.
M KähönenUniversity of Tampere, Tampere, Finland.
T LehtimäkiFinnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
N Hutri-KähönenUniversity of Tampere, Tampere, Finland.
O RaitakariDepartment of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
M JuonalaDepartment of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
Tampere University · FIUniversity of Helsinki · FITurku University Hospital · FIRoyal Children's Hospital · AUUniversity of Eastern Finland · FIUniversity of Turku · FIVaasa Central Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic oral infection/inflammation is cross-sectionally associated with metabolic syndrome (MetS) in adults, but there are few longitudinal studies and studies on childhood oral infections and adult MetS risk. We investigated whether childhood clinical parameters indicative of oral infection/inflammation were associated with adulthood MetS and its components. A total of 755 children aged 6, 9, and 12 y underwent a clinical oral examination in 1980 as part of the Cardiovascular Risk in Young Finns Study. Oral health measures included bleeding on probing (BOP), periodontal probing pocket depth, caries, fillings, and visible plaque. Metabolic parameters were determined at baseline and during follow-up. MetS was diagnosed (

Indexed as

InfectionsMetabolic SyndromeMouth DiseasesAdultChildCohort StudiesDiagnosis, OralFinlandHumansInflammationLongitudinal StudiesMaleRisk Factorscariesgingivitisinflammationpediatric dentistryperiodontal disease(s)periodontitis

Identifiers

PMID32479136
PMCPMC7443963
OpenAlexW3023446733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.