Evidence map›Paper›PMID 32478971›Full record

ReviewDermatologic therapy2020

Psoriatic arthritis and COVID-19 pandemic: Consequences in medical treatment?

Uwe Wollina, Massimo Fioranelli, Mohamad Goldust, Torello Lotti

Open access · bronzeAbstract readReview
In one paragraph

Review in Dermatologic therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Inflammation Causes Exacerbation of COVID-19: How about Skin Inflammation?International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Uwe WollinaDepartment of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.ORCID 0000-0001-5933-2913
Massimo FioranelliDepartment of Nuclear Physics, Sub-Nuclear and Radiation, G. Marconi University, Rome, Italy.ORCID 0000-0002-1319-8779
Mohamad GoldustDepartment of Dermatology, University of Rome G. Marconi, Rome, Italy.ORCID 0000-0002-9615-1246
Torello LottiDepartment of Dermatology, University of Studies Guglielmo Marconi, Rome, Italy.ORCID 0000-0003-0840-1936
Marconi University · ITJohannes Gutenberg University Mainz · DEStädtisches Klinikum Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has a strong negative impact on human society worldwide. Patients with immune-mediated disease may be prone to an increased risk of infection and/or more severe course. We review the available data for patients with psoriatic arthritis (PSA) and systemic treatments. Current treatment options are summarized. Based upon the experience with COVID-19, the following problems are addressed: (a) Can systemic treatment reduce comorbidities of PsA that are also comorbidities for COVID-19? Does systemic medical treatment pose an increased risk of infection with SARS-CoV-2? Does systemic drug therapy have an impact on the risk of pulmonary fibrosis-a factor with strong negative impact on COVID-19 outcome? Small molecules, inhibitors of tumor necrosis factor alfa, interleukin, and JAK inhibitors are considered. The data are inhomogeneous for the multiple drugs used in PsA. Although the risk for severe upper airway tract infections during clinical controlled trials was mostly in the range of placebo, these data have been obtained before the COVID-19 pandemic and should be interpreted with caution. Some biologics demonstrated an antifibrotic activity in vitro and in animal disease models. None of the biologics is indicated during an active infection with fever. In nonsymptomatic PsA patients, systemic drug therapy can be continued.

Indexed as

SARS-CoV-2Arthritis, PsoriaticBiological ProductsComorbidityCOVID-19HumansJanus Kinase InhibitorsTumor Necrosis Factor-alphaBiological ProductsJanus Kinase InhibitorsTumor Necrosis Factor-alphabiologicsCOVID-19psoriatic arthritissmall moleculessystemic medical treatment

Identifiers

PMID32478971
PMCPMC7300518
OpenAlexW3031200472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.