SynthesisJAMA pediatrics2020
Youth and Young Adult Use of Pod-Based Electronic Cigarettes From 2015 to 2019: A Systematic Review.
Synthesis in JAMA pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Peer Influence and Use of Electronic Cigarettes among Adolescents and Young Adults: A Meta-Analysis of Prospective Studies.Asian Pacific journal of cancer prevention : APJCP · 2025Pooled it
- Chemical Profiles and Toxicity of Electronic Cigarettes: An Umbrella Review and Methodological Considerations.International journal of environmental research and public health · 2023Pooled it
- Reporting and methodological quality of systematic literature reviews evaluating the associations between e-cigarette use and cigarette smoking behaviors: a systematic quality review.Harm reduction journal · 2021Pooled it
- Abuse Liability of Electronic Cigarettes in Never-Smoking Electronic Cigarette Users.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Trial
- Electronic cigarette use, related health outcomes and policy interventions in the USA: a call for research to fill evidence gaps.Tobacco control · 2026Review
- Narrative Review of Novel Nicotine-Delivery Systems and Emerging Pharmaceuticals for Tobacco Cessation.Medicines (Basel, Switzerland) · 2026Review
- Trends in e-cigarette research in Korea: a comparative analysis of adult and adolescent studies.Child health nursing research · 2026Article
- Comparison of Elicit AI and Traditional Literature Searching in Evidence Syntheses Using Four Case Studies.Cochrane evidence synthesis and methods · 2025Article
- Reasons for using e-cigarettes among adults who smoke: comparing the findings from the 2016 and 2020 ITC Korea Surveys.Tobacco control · 2025Article
- Building consensus on a set of ENDS-specific pictorial health warnings: a Delphi study among a tobacco control expert panel.Tobacco control · 2025Article
- Electronic Cigarette-Derived Metals: Exposure and Health Risks in Vapers.Chemical research in toxicology · 2025Review
- Article
- Prevalence and correlates of negative side effects from vaping nicotine: Findings from the 2020 ITC four country smoking and vaping survey.Drug and alcohol dependence · 2025Article
- "If I could try it, I'd try it": Qualitative study of the illegal vaping culture in Singapore.Addictive behaviors reports · 2024Article
- How Do Adolescent Smoking Prevention Interventions Work in Different Contextual Settings? A Qualitative Comparative Study Between the UK and Colombia.International journal of behavioral medicine · 2024Article
- Physical and Chemical Characterization of Aerosols Produced from Experimentally Designed Nicotine Salt-Based E-Liquids.Chemical research in toxicology · 2024Article
- Current perspective on e-cigarette use and respiratory outcomes: mechanisms and messaging.Expert review of respiratory medicine · 2024Review
- Altered insular functional activity among electronic cigarettes users with nicotine dependence.Translational psychiatry · 2024Article
- The commercial promotion of electronic cigarettes on social media and its influence on positive perceptions of vaping and vaping behaviours in Anglophone countries: A scoping review.PLOS global public health · 2024Article
- Assessing the public discourse on Twitter: Reactions to the JUUL e-cigarettes ban in the United States.Tobacco induced diseases · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Importance: The use of electronic cigarettes (e-cigarettes) has rapidly increased among youth and young adults, but knowledge gaps exist on the potential health effects of using recently introduced pod-based e-cigarettes. Objective: To conduct a systematic review of recent peer-reviewed scientific literature on pod-based e-cigarettes. Evidence Review: A search of online databases, including PubMed, Web of Science, Embase, and EBSCO HOST, was conducted to identify pod-based e-cigarette-associated articles from June 2015 (the time when JUUL [JUUL Labs] was introduced) to June 2019. We included English-language articles that presented primary data on pod-based e-cigarettes. Findings: Pod-based e-cigarettes represent a substantial evolution in design by increasing the efficient delivery of nicotine. While these products may contain less harmful constituents than other types of e-cigarettes and cigarettes, there is no evidence that the levels found are safe among youth. There is evidence for higher nicotine dependence associated with their use. Pod-based e-cigarette brands, compared with other e-cigarette brands, have targeted youth and young adults with social media marketing. There was less discussion about the use of these products as smoking cessation devices or their health risks on social media. The social acceptability and favorable perceptions of pod-based e-cigarettes may underlie the use of these products. Conclusions and Relevance: The appeal and dependence potential of pod-based e-cigarettes for youth emphasize the need for stronger regulations on product design, social media, marketing channels, and youth access together with health communications that emphasize the risks of nicotine dependence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.