ArticleBrain and behavior2020
Clinical relevance of serum omentin-1 levels as a biomarker of prognosis in patients with acute cerebral infarction.
Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 16 citations in OpenAlex.
- Histone demethylase JMJD1C advances macrophage foam cell formation and atherosclerosis progression by promoting the transcription of PCSK9.Journal of physiology and biochemistry · 2025Article
- Analysis of 90-day risk factors for poor prognosis in patients with postoperative CT with hyperdense signs after thrombectomy for acute ischemic stroke.Frontiers in neurology · 2025Article
- Adipokines in the Crosstalk between Adipose Tissues and Other Organs: Implications in Cardiometabolic Diseases.Biomedicines · 2024Review
- The Role of Adipokines in the Pathologies of the Central Nervous System.International journal of molecular sciences · 2023Review
- Neuroinflammation-associated miR-106a-5p serves as a biomarker for the diagnosis and prognosis of acute cerebral infarction.BMC neurology · 2023Article
- The Role of Adipokines in Inflammatory Mechanisms of Obesity.International journal of molecular sciences · 2022Review
- Article
- The Effect of the Ketogenic Diet on Adiponectin, Omentin and Vaspin in Children with Drug-Resistant Epilepsy.Nutrients · 2022Article
- The Role of Anti-Inflammatory Adipokines in Cardiometabolic Disorders: Moving beyond Adiponectin.International journal of molecular sciences · 2021Review
- Omentin Is Independently Associated with Stroke Severity and Ipsilateral Carotid Artery Stenosis in Patients with Acute Cerebral Ischemia.Journal of clinical medicine · 2021Article
- Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells.Frontiers in cell and developmental biology · 2021Article
- Clinical relevance of serum omentin-1 levels as a biomarker of prognosis in patients with acute cerebral infarction.Brain and behavior · 2020Article
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2 authors at 1 institution in 1 country.
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Abstract
background and purposePrevious studies have shown that adipocytokines are associated with atherosclerosis, diagnosis, and functional prognosis after ischemic stroke. However, few studies have investigated the relationship between omentin-1 and atherosclerotic acute cerebral infarction (ACI).
methodsIn this study, we investigated the association between serum omentin-1 levels at admission and severity, infarction volume, and functional prognosis of patients 90 days after atherosclerotic ACI.
resultsA total of 109 patients with atherosclerotic ACI were enrolled. Serum omentin-1 levels at admission were lower in patients with ACI than those in healthy controls (47.18 ± 13.64 vs. 56.27 ± 34.44 ng/ml, p = .014). Serum omentin-1 levels at admission were negatively correlated with severity of ACI (r = -.271, p = .004) and infarction volume (r = -.264, p = .006), respectively. Moreover, serum omentin-1 levels were lower in the poor functional prognosis group than those in the good functional prognosis group in patients with large artery and small artery atherosclerotic ACI. In a logistic regression analysis, higher serum omentin-1 level (>43.10 ng/ml) at admission was negatively associated with a poor functional prognosis 90 days after atherosclerotic ACI.
conclusionsSerum omentin-1 levels at admission were significantly lower among patients with ACI. A higher plasma omentin-1 level (>43.10 ng/ml) was negatively associated with poor functional prognosis 90 days after atherosclerotic ACI. Further studies are needed to investigate the pathophysiological mechanism of omentin-1 in affecting attacks and prognosis of ACI as well as to confirm the value of plasma omentin-1 level as a potential biomarker.
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