Evidence map›Paper›PMID 32478442›Full record

ArticleHead & neck2020

Physical inactivity and head and neck cancer mortality.

Jacob Fried, John Lewis Etter, Ashley E Stenzel, Janine M Joseph, Rikki Cannioto, Iris R Danziger, Kirsten B Moysich

Abstract read
In one paragraph

Article in Head & neck, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effects of exercise on head and neck cancer surgery: a systematic review of randomized controlled trials.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. The Use of Photodynamic Therapy for Head, Neck, and Brain Diseases.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jacob FriedJacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
John Lewis EtterJacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Ashley E StenzelDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer, Buffalo, New York, USA.
Janine M JosephDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer, Buffalo, New York, USA.
Rikki CanniotoDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer, Buffalo, New York, USA.
Iris R DanzigerDepartment of Otolaryngology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Kirsten B MoysichDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer, Buffalo, New York, USA.ORCID 0000-0002-4678-2058

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
Interdisciplinary Training in Cancer Epidemiology at UBT32CA113951 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI FREUDENHEIM, JO L., MOYSICH, KIRSTEN B. · 2017 to 2021
$693k
NCI NIH HHS P30 CA016056NCI NIH HHS T32 CA113951
6 · The paper itself

Abstract

backgroundThis study was performed to examine the association between adulthood recreational physical inactivity (PIA) and mortality among patients with cancers of the head and neck.

methodsPatients with head and neck cancer at Roswell Park between years 1990 to 1998 were included (N = 305). Multivariable Cox proportional hazard ratios (HR) with corresponding 95% confidence intervals (CI) were used to analyze the association between PIA and risk of dying.

resultsThere was a 1.40-fold increase in risk of dying among PIA patients, when compared to active patients with head and neck cancers (HR = 1.40, CI: 1.03-1.91). This was observed greater in PIA women (HR = 2.40, CI: 1.28-4.52), patients who were overweight/obese (HR = 1.76, CI: 1.09-2.85), patients with pharynx as the primary site (HR = 1.85, CI: 1.01-3.38), and patients with distant metastasis (HR = 5.19, CI: 1.37-19.65).

conclusionPhysically inactive patients with head and neck cancers are at significantly greater risk of dying when compared to patients who are active.

Indexed as

Head and Neck NeoplasmsSedentary BehaviorAdultFemaleHumansObesityOverweightProportional Hazards ModelsRisk Factorshead and neck cancermortalityphysical inactivity

Identifiers

PMID32478442
PMCPMC8393317

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.