ArticleMedicine and pharmacy reports2020
Risk assessment for osteoradionecrosis of the jaws in patients with head and neck cancer.
Article in Medicine and pharmacy reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Identifying risk factors for osteoradionecrosis of the jaws: a systematic review and meta-analysis.Clinical oral investigations · 2026Pooled it
- Osteoradionecrosis After Modern Radiotherapy for Oral Cavity Cancer: Incidence and Risk Factors.Laryngoscope investigative otolaryngology · 2026Article
- Article
- Risk factors associated with prognosis in patients with osteoradionecrosis of the jaws: A single institutional experience over 15 years.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Prevention of osteoradionecrosis in patients with head and neck cancer treated with radiation therapy.Head & neck · 2025Article
- Osteoradionecrosis in osseous free flaps after maxillofacial reconstruction: a single-center experience.Frontiers in oncology · 2025Article
- The relevance of dental management prior to radiation therapy with severe oral mucositis in head and neck cancer patients.Journal of dental sciences · 2025Article
- Risk factor analysis and development of predictive models for osteoradionecrosis in patients with nasopharyngeal carcinoma after concurrent chemoradiotherapy.American journal of cancer research · 2024Article
- Palliative oral care in patients undergoing radiotherapy: Integrated review.Journal of family medicine and primary care · 2020Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo identify the potential risk factors for the occurrence of osteoradionecrosis (ORN) of the jaws among patients who have been treated with radiotherapy for head and neck malignancy.
methodsThe study comprised of 231 patients treated with radiotherapy for head and neck malignancy at a tertiary referral center. The following details were recorded for each patient: age, gender, histopathological diagnosis, clinical staging, tumor site, treatment modality, radiation dose, radiation field, number of fractions, type of accelerator used, radiation area and duration of follow-up. Patient's tobacco, alcohol habit history, and history of extraction of teeth before/during/after radiotherapy were also noted.
resultsThirteen patients had osteoradionecrosis (frequency 5.62%). Among the radiotherapy variables assessed, increased radiation area was found to be significantly associated with the occurrence of osteoradionecrosis. Among the 13 ORN cases, 10 (76.9%) had a history of tobacco consumption, 8 (61.5%) had a time interval between radiotherapy and occurrence of ORN of less than 1-year duration.
conclusionsWe found a low cumulative incidence of osteoradionecrosis and a tendency to occur within a year of starting radiotherapy. Patients of older age, those with a prior tobacco habit may be considered more liable to develop osteoradionecrosis. A larger radiation field may also put patients at hazard for developing osteoradionecrosis.
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