Evidence map›Paper›PMID 32478277›Full record

ArticleACS omega2020

Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health.

Bahare Salehi, Laura Machin, Lianet Monzote, Javad Sharifi-Rad, Shahira M Ezzat, Mohamed A Salem, Rana M Merghany, Nihal M El Mahdy, Ceyda Sibel Kılıç, Oksana Sytar and 5 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 265 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
265citing papers in PubMed, 4 pooled it
30.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

265 citing papers in PubMed, 4 syntheses or guidelines pooled it, 661 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. The effect of quercetin and citrulline on cycling time trial performance.Journal of the International Society of Sports Nutrition · 2024
    Trial
  7. The logarithmic phase as a therapeutic direction: evaluating pharmacological strategies against cancer progression.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  8. Review
  9. International journal of molecular sciences · 2026
    Article
  10. Review
  11. Flavonoids: Hemorheological effects and mechanisms of action.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  12. Review
  13. Review
  14. Ubiquitination-Related Diagnostic Biomarkers for Diabetic Nephropathy: Insights From Multiomic Analysis, Drug Docking, and Experimental Validation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  15. Article
  16. Quercetin ReducesInternational journal of molecular sciences · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Review

205 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 15 institutions in 10 countries.

Bahare SalehiStudent Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran.
Laura MachinInstitute of Pharmacy and Food, University of Havana, Havana, Cuba.
Lianet MonzoteParasitology Department, Institute of Medicine Tropical Pedro Kourí, Havana, Cuba.
Javad Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran.
Shahira M EzzatDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt.
Mohamed A SalemDepartment of Pharmacognosy, Faculty of Pharmacy, Menoufia University, Gamal Abd El Nasr st., Shibin Elkom, Menoufia 32511, Egypt.
Rana M MerghanyDepartment of Pharmacognosy, National Research Centre, Giza 12622, Egypt.
Nihal M El MahdyDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6th of October 12566, Egypt.
Ceyda Sibel KılıçDepartment of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University, Ankara 06100, Turkey.
Oksana SytarDepartment of Plant Biology Department, Institute of Biology, Taras Shevchenko National University of Kyiv, Volodymyrska str., 64, Kyiv 01033, Ukraine.
Mehdi Sharifi-RadDepartment of Medical Parasitology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman 7616913555, Iran.
Farukh SharopovDepartment of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, Dushanbe 734003, Tajikistan.
Natália MartinsFaculty of Medicine, University of Porto, Porto 4200-319, Portugal.
Miquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, and Centre for Healthy Living, University of Concepción, Concepción 4070386, Chile.
William C ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong.
Ankara University · TRBam University of Medical Sciences · IRCairo University · EGInstituto de Medicina Tropical “Pedro Kourí” · CUKerman University of Medical Sciences · IRMenoufia University · EGNational Research Centre · EGOctober University of Modern Sciences and Arts · EGQueen Elizabeth Hospital · CNShahid Beheshti University of Medical Sciences · IRSlovak University of Agriculture in Nitra · SKTajik State Medical University · TJUniversidade do Porto · PTUniversity of Concepción · CLUniversity of Havana · CU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, and wound-healing effects of Que have been extensively investigated, as well as its anticancer activity against different cancer cell lines has been recently reported. Que and its derivatives are found predominantly in the Western diet, and people might benefit from their protective effect just by taking them via diets or as a food supplement. Bioavailability-related drug-delivery systems of Que have also been markedly exploited, and Que nanoparticles appear as a promising platform to enhance their bioavailability. The present review aims to provide a brief overview of the therapeutic effects, new insights, and upcoming perspectives of Que.

Identifiers

PMID32478277
PMCPMC7254783
OpenAlexW3024750580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.