ArticleJournal of animal science and biotechnology2020
Optimal dietary copper requirements and relative bioavailability for weanling pigs fed either copper proteinate or tribasic copper chloride.
Article in Journal of animal science and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Comparative Effects of Copper Glycinate and Potassium Diformate on Immunity and Gut Microbiota of Pigs-Potential Analysis of Potassium Diformate as a Copper Additive Substitute.Animals : an open access journal from MDPI · 2026Article
- Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs.NPJ biofilms and microbiomes · 2026Article
- Evaluation of copper feeding strategies and sources on nursery and finishing pig performance.Translational animal science · 2026Article
- Effects of Dietary Copper Sources and Levels on Liver Copper Metabolism and the Expression of Transporters in Growing Pigs.Animals : an open access journal from MDPI · 2025Article
- Potentiated zinc and monovalent copper oxide as dietary supplements for weanling piglets: effects on systemic and mucosal immunity, gut permeability, and fecal microbiota composition.Frontiers in veterinary science · 2025Article
- A Systematic Review and Meta-Analysis of the Effects of Various Sources and Amounts of Copper on Nursery Piglets.Veterinary sciences · 2024Article
- Assessment of the application for renewal of the authorisation of a feed additive consisting of dicopper chloride trihydroxide for all animal species (Nutreco Nederland B.V.).EFSA journal. European Food Safety Authority · 2023Article
- Blocked conversion of Lactobacillus johnsonii derived acetate to butyrate mediates copper-induced epithelial barrier damage in a pig model.Microbiome · 2023Article
- Ionomics-metabolome association analysis as a new approach to the impact of dietary copper levels in suckling piglets model.Scientific reports · 2023Article
- Dietary supplementation with nano-composite of copper and carbon on growth performance, immunity, and antioxidant ability of yellow-feathered broilers.Journal of animal science · 2023Article
- Relative Bioavailability of Trace Minerals in Production Animal Nutrition: A Review.Animals : an open access journal from MDPI · 2022Review
- Determination of dietary copper requirement by the monoamine oxidase activity in kidney of broilers from 1 to 21 days of age.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- Different copper sources and levels affect growth performance, copper content, carcass characteristics, intestinal microorganism and metabolism of finishing pigs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- Fecal microbiome shifts by different forms of copper supplementations in growing pigs.Journal of animal science and technology · 2021Article
- Development of an Immunoassay for the Detection of Copper Residues in Pork Tissues.Biosensors · 2021Article
- Digestibility and metabolism of copper in diets for pigs and influence of dietary copper on growth performance, intestinal health, and overall immune status: a review.Journal of animal science and biotechnology · 2021Review
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to determine the effects of supplementing Cu on growth performance, Cu metabolism and Cu-related enzyme activities of weanling pigs fed diets with two different Cu sources, and to estimate optimal Cu requirements and relative bioavailability from these two sources for pigs.
methodsWeanling pigs were allocated to 14 treatments arranged factorially, including 6 added Cu levels (5, 10, 20, 40, 80, 160 mg/kg), and 2 mineral sources (tribasic Cu chloride, TBCC and copper proteinate, CuPro), as well as one negative control (0 mg/kg added Cu level) and one maximum allowed level treatment (200 mg/kg TBCC) for the entire 38-d experiment. Growth performance, mineral status and enzyme activities were measured at the end of this study.
resultsIncreasing levels of Cu showed linear and quadratic responses (
conclusionThe findings indicated that Cu recommendation from current NRC (5-6 mg/kg) was not sufficient to meet the high requirement of weanling pigs. Cu from CuPro was significantly more bioavailable to weanling pigs than TBCC in stimulating growth and enzyme activities, decreasing diarrhea frequency and fecal Cu contents to the environment.
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