Evidence map›Paper›PMID 32477460›Full record

ArticleOncotarget2020

Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults.

Hirotomo Yamanashi, Kenji Nagaoki, Sinsuke Kanbara, Yuji Shimizu, Kunihiko Murase, Akira Tsujino, Takahiro Maeda

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hirotomo YamanashiDepartment of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
Kenji NagaokiNagasaki Prefecture Goto Central Hospital, Goto, Nagasaki, Japan.
Sinsuke KanbaraNagasaki Prefecture Goto Central Hospital, Goto, Nagasaki, Japan.
Yuji ShimizuDepartment of Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
Kunihiko MuraseNagasaki Prefecture Goto Central Hospital, Goto, Nagasaki, Japan.
Akira TsujinoDepartment of Neurology and Strokology, Nagasaki University Hospital, Sakamoto, Nagasaki, Japan.
Takahiro MaedaDepartment of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
Nagasaki University · JPNagasaki University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLower handgrip strength is a manifestation of sarcopenia and frailty, and has been reported to be associated with cerebral microbleeds (CMBs), which appear on T2 MATERIALS AND

methodsWe conducted a cross-sectional study of 95 60- to 87-year-old Japanese people who underwent brain magnetic resonance imaging in 2016-2017. Baseline information was obtained by trained interviewers regarding the age, sex, smoking status, nutrient intake, cognition, medical history, education, and household income of the participants. Physical activity was assessed using a tri-axial accelerometer. We used the Fried frailty phenotype definition. Multivariable linear regression analysis was performed.

resultsHandgrip strength was independently associated with the presence of CMB after adjustment for age, sex, body mass index, classical cardiovascular risk factors, protein intake, and daily activity (B = -3.43,

conclusionsPlatelet count, a marker of vascular repair capability, appears to modify the relationship between handgrip strength and CMBs.

Indexed as

cerebral microbleedsfrailtyhandgrip strengthplateletsarcopenia

Identifiers

PMID32477460
PMCPMC7233806
OpenAlexW3024182420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.