ArticleInfectious agents and cancer2020
Risk of cervical lesions in high-risk HPV positive women with normal cytology: a retrospective single-center study in China.
Article in Infectious agents and cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The pattern of human papillomavirus infection and genotypes among Nigerian women from 1999 to 2019: a systematic review.Annals of medicine · 2021Pooled it
- Evaluation of the Outcomes of Patients Undergoing Colposcopy for High-Risk Human Papillomavirus Positivity and/or Abnormal Cervical Cytology.Diagnostics (Basel, Switzerland) · 2026Article
- Minimally invasive diagnosis of precancerous cervical lesions using single-cell peripheral immune atlas.Cell reports. Medicine · 2025Article
- Post-conization pathological upgrading and outcomes of 466 patients with low-grade cervical intraepithelial neoplasia.Frontiers in oncology · 2024Article
- Factors Associated with Cyto-Histological Misinterpretation of Cervical Smear according to Menopausal Status.Journal of menopausal medicine · 2022Article
- Which is the best management for women with normal cervical cytologic findings despite positivity for non-16/18 high risk human papillomaviruses?Frontiers in public health · 2022Review
- The performance of Cobas HPV test for cervical cancer screening in Chinese female migrant workers.Epidemiology and infection · 2021Article
- Triaging HPV-positive, cytology-negative cervical cancer screening results with extended HPV genotyping and p16BMC infectious diseases · 2021Observational
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate high-risk HPV (hr-HPV) genotype distributions and the association between hr-HPV infection with severity of the cervical lesions in women with normal cytology.
methodsIn this cross-sectional study, the result of the hr-HPV test and biopsy of colposcopy of women with normal cytology from January 2012 to January 2019 were analyzed. The detection rate of high-grade squamous intraepithelial lesion (HSIL) and cervical cancer were calculated among different hr-HPV genotypes, viral load group, and age groups.
resultsFive thousand eight hundred eighty women were enrolled in this study. Overall, 59.97% had normal histological results, 19.32% had HSIL, and 1.07% had cervical cancer. The detection rate of HSIL or worse (HSIL+) in women with single HPV16(34.00%), HPV31(27.50%), HPV33(25.58%), and HPV52(20.88%) infection were higher significantly than single HPV18 (15.59%) infection, respectively. The HSIL+ detection rate between HPV16 single infection and multiple infections (excluding HPV18) was no significant difference (34% vs 35.47%,
conclusionWomen who have normal cytology with HPV 16/18/31/33/52/58 infections, multiple HPV infections and high viral load, have a higher detection rate of HSIL+.
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