Evidence map›Paper›PMID 32477244›Full record

ArticleFrontiers in neurology2020

Increased Otolin-1 in Serum as a Potential Biomarker for Idiopathic Benign Paroxysmal Positional Vertigo Episodes.

Yunqin Wu, Weiwei Han, Wang Yan, Xiaoxiong Lu, Min Zhou, Li Li, Qiongfeng Guan, Zhenyi Fan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05446506 (Comparative Study for Serum Levels of Otolin-1 and Vitamin D in pre-and Post-treatments of Patients With Benign Paroxysmal Positional Vertigo), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05446506 completednot on this mapstarted 2021, after this paper: background citation

Comparative Study for Serum Levels of Otolin-1 and Vitamin D in pre-and Post-treatments of Patients With Benign Paroxysmal Positional Vertigo

TypeobservationalSponsorChiang Mai UniversityRan2021 to 2023Enrolled21ConditionsBenign Paroxysmal Positional Vertigo
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Blood Biomarkers for the Diagnosis of Peripheral Causes of Vestibular Syndrome: A Systematic Review and Meta-Analysis.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2025
    Pooled it
  2. Pooled it
  3. Serum otolin-1 levels in vestibular migraine and Ménière's disease: a comparative clinical study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
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  10. Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission.International archives of otorhinolaryngology · 2023
    Article
  11. Article
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  13. Advances in otolith-related protein research.Frontiers in neuroscience · 2022
    Review
  14. Article
  15. Natural Mutations Affect Structure and Function of gC1q Domain of Otolin-1.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yunqin WuDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Weiwei HanDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Wang YanDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Xiaoxiong LuDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Min ZhouDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Li LiDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Qiongfeng GuanDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Zhenyi FanDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

benign paroxysmal positional vertigobiomarkerotoconiaotolin-1vertigo

Identifiers

PMID32477244
PMCPMC7237635
OpenAlexW3017032063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.