Evidence map›Paper›PMID 32477159›Full record

ArticleFrontiers in physiology2020

Experimental Subarachnoid Hemorrhage Drives Catecholamine-Dependent Cardiac and Peripheral Microvascular Dysfunction.

Danny D Dinh, Darcy Lidington, Jeffrey T Kroetsch, Chloe Ng, Hangjun Zhang, Sergei A Nedospasov, Scott P Heximer, Steffen-Sebastian Bolz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Danny D DinhDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Darcy LidingtonDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Jeffrey T KroetschDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Chloe NgDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Hangjun ZhangDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Sergei A NedospasovEngelhardt Institute of Molecular Biology, Moscow, Russia.
Scott P HeximerDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Steffen-Sebastian BolzDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
University of Toronto · CATed Rogers Centre for Heart Research · CAHeart and Stroke Foundation · CASirius University of Science and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subarachnoid hemorrhage (SAH) is a devastating cerebral event caused by an aneurysmal rupture. In addition to neurological injury, SAH has significant effects on cardiac function and the peripheral microcirculation. Since these peripheral complications may exacerbate brain injury, the prevention and management of these peripheral effects are important for improving the overall clinical outcome after SAH. In this investigation, we examined the effects of SAH on cardiac function and vascular reactivity in a well-characterized blood injection model of SAH. Standard echocardiographic and blood pressure measurement procedures were utilized to assess cardiac function and hemodynamic parameters

Indexed as

adrenergic signalingmechanosensormyocardial stunningmyogenic responsetumor necrosis factor

Identifiers

PMID32477159
PMCPMC7237757
OpenAlexW3025717036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.