ArticleFrontiers in neuroscience2020
Closed-Loop Transcranial Ultrasound Stimulation for Real-Time Non-invasive Neuromodulation
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Focused ultrasound for treatment of epilepsy: a systematic review and meta-analysis of preclinical and clinical studies.Neurosurgical review · 2024Pooled it
- Integrating neural decoding, memristive materials, and adaptive control frameworks for next-generation hippocampal memory prosthetics.iScience · 2026Review
- Review
- Transcranial focused ultrasound stimulation in schizophrenia: current evidence, mechanisms, and future directions.Frontiers in psychiatry · 2026Review
- Transcranial Focused Ultrasound Stimulation Targeting White Matter Inhibits Seizures in a Rat Model of Epilepsy.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Parameter-Determined Effects: Advances in Transcranial Focused Ultrasound for Modulating Neural Excitation and Inhibition.Bioengineering (Basel, Switzerland) · 2025Review
- Towards an ion-channel-centric approach to ultrasound neuromodulation.Current opinion in behavioral sciences · 2024Article
- The Associative Thalamus: A Switchboard for Cortical Operations and a Promising Target for Schizophrenia.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024Review
- Therapeutic ultrasound: an innovative approach for targeting neurological disorders affecting the basal ganglia.Frontiers in neuroanatomy · 2024Review
- Article
- Ultrasound Neuromodulation as a New Brain Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- The Emergence of Functional Ultrasound for Noninvasive Brain-Computer Interface.Research (Washington, D.C.) · 2023Review
- Transcranial low-intensity ultrasound stimulation for treating central nervous system disorders: A promising therapeutic application.Frontiers in neurology · 2023Review
- Ultrasonic therapies for seizures and drug-resistant epilepsy.Frontiers in neurology · 2023Review
- General-Purpose Ultrasound Neuromodulation System for Chronic, Closed-Loop Preclinical Studies in Freely Behaving Rodents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Low-Intensity Transcranial Ultrasound Stimulation: Mechanisms of Action and Rationale for Future Applications in Movement Disorders.Brain sciences · 2022Review
- Focusing in on the Future of Focused Ultrasound as a Translational Tool.Brain sciences · 2022Review
- Control of inflammation using non-invasive neuromodulation: past, present and promise.International immunology · 2022Review
- Phase-locked closed-loop ultrasound stimulation modulates theta and gamma rhythms in the mouse hippocampus.Frontiers in neuroscience · 2022Article
- Transcranial Focused Ultrasound Enhances Sensory Discrimination Capability through Somatosensory Cortical Excitation.Ultrasound in medicine & biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The closed-loop brain stimulation technique plays a key role in neural network information processing and therapies of neurological diseases. Transcranial ultrasound stimulation (TUS) is an established neuromodulation method for the neural oscillation in animals or human. All available TUS systems provide brain stimulation in an open-loop pattern. In this study, we developed a closed-loop transcranial ultrasound stimulation (CLTUS) system for real-time non-invasive neuromodulation
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.