ArticleFrontiers in neuroscience2020
Compensatory Cross-Modal Plasticity Persists After Sight Restoration.
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Interim safety and efficacy of gene therapy for RLBP1-associated retinal dystrophy: a phase 1/2 trial.Nature communications · 2024Trial
- Visual experience shapes functional connectivity between occipital and non-visual networks.eLife · 2026Article
- Simulated prosthetic vision confirms checkerboard as an effective raster pattern for epiretinal implants.Journal of neural engineering · 2025Article
- Visual cortical thickness increases with prolonged artificial vision restoration.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- The efficiency of sensory systems in postural control of children with and without hearing or visual impairments.PloS one · 2025Article
- fNIRS Changes in the Middle Temporal and Occipital Cortices After a Cochlear Implant.The Laryngoscope · 2025Article
- Motor Processing in Children With Cochlear Implants as Assessed by Functional Near-Infrared Spectroscopy.Perceptual and motor skills · 2024Article
- The amplitude of low frequency fluctuation and spontaneous brain activity alterations in age-related macular degeneration.Frontiers in medicine · 2024Article
- How learning to read Braille in visual and tactile domains reorganizes the sighted brain.Frontiers in neuroscience · 2024Article
- Crossmodal plasticity in hearing loss.Trends in neurosciences · 2023Review
- Implications of Neural Plasticity in Retinal Prosthesis.Investigative ophthalmology & visual science · 2022Article
- Focusing on cognitive potential as the bright side of mental atypicality.Communications biology · 2022Review
- Visual-tactile shape perception in the visually restored with artificial vision.Journal of vision · 2022Article
- Sight restoration reverses blindness-induced cross-modal functional connectivity changes between the visual and somatosensory cortex at rest.Frontiers in neuroscience · 2022Article
- Multisensory perception in Argus II retinal prosthesis patients: Leveraging auditory-visual mappings to enhance prosthesis outcomes.Vision research · 2021Article
- Structural Differences Across Multiple Visual Cortical Regions in the Absence of Cone Function in Congenital Achromatopsia.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Sensory deprivation prompts extensive structural and functional reorganizations of the cortex resulting in the occupation of space for the lost sense by the intact sensory systems. This process, known as cross-modal plasticity, has been widely studied in individuals with vision or hearing loss. However, little is known on the neuroplastic changes in restoring the deprived sense. Some reports consider the cross-modal functionality maladaptive to the return of the original sense, and others view this as a critical process in maintaining the neurons of the deprived sense active and operational. These controversial views have been challenged in both auditory and vision restoration reports for decades. Recently with the approval of Luxturna as the first retinal gene therapy (GT) drug to reverse blindness, there is a renewed interest for the crucial role of cross-modal plasticity on sight restoration. Employing a battery of task and resting state functional magnetic resonance imaging (rsfMRI), in comparison to a group of sighted controls, we tracked the functional changes in response to auditory and visual stimuli and at rest, in a group of patients with biallelic mutations in the
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.