ArticleColombia medica (Cali, Colombia)2019
Association between metabolic syndrome and euthyroid nodular goiter: a case-control study.
Article in Colombia medica (Cali, Colombia), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- The Relationship and Gender Disparity Between Thyroid Nodules and Metabolic Syndrome Components Based on a Recent Nationwide Cross-Sectional Study and Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Association of Central Obesity and Diabetes with Thyroid Nodules: A 3.2-year Prospective Study in Chinese Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Prevalence and predictors of thyroid nodules among adults: analyzing the association with metabolic syndrome in a cross-sectional study.BMC endocrine disorders · 2025Article
- Ultrasonic Imaging of Insulin Resistance (HOMA-IR) and Metabolic Syndrome with and without Thyroid Nodules: A Case-Control Patient-Based Study.Advanced biomedical research · 2025Article
- Stages of benign thyroid nodules: principles and ultrasound signs.Quantitative imaging in medicine and surgery · 2024Review
- Impact of metformin on hypothalamic-pituitary-thyroid axis activity in women with autoimmune and non-autoimmune subclinical hypothyroidism: a pilot study.Pharmacological reports : PR · 2024Article
- Associations of Combined Exposure to Metabolic and Inflammatory Indicators with Thyroid Nodules in Adults: A Nested Case-Control Study.International journal of endocrinology · 2024Article
- Establishment and validation of a multivariate logistic model for risk factors of thyroid nodules using lasso regression screening.Frontiers in endocrinology · 2024Article
- Evaluation of Insulin Resistance (HOMA-IR) for Patients with and without Thyroid Nodules: A Patient-Based Study.Advanced biomedical research · 2023Article
- Glucose Metabolism Derangements and Thyroid Nodules: Does Sex Matter?Journal of personalized medicine · 2022Article
- Presence of Metabolic Syndrome and Thyroid Nodules in Subjects with Colorectal Polyps.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic syndrome is a cluster of metabolic abnormalities and abdominal obesity; its pathophysiologic basis, insulin resistance, has been shown to act as agent in thyroid cell proliferation. Few studies analyze the relationship between metabolic syndrome and thyroid nodular disease, with a substantial knowledge gap.
objectiveDetermine the association between metabolic syndrome and nodular thyroid disease in a region with adequate iodine intake.
methodsCase-control study. A total of 182 patients referred to radiology to undergo thyroid ultrasonography due to suspicion of thyroid disease. Cases had at least one thyroid nodule greater than 3 mm (n= 91). Controls did not have evidence of thyroid nodules (n= 91).
resultsBivariate analysis showed a significant association between metabolic syndrome and the presence of thyroid nodule (OR 2.56, 95% CI: 1.41-4.66,
conclusionThe thyroid nodular disease is associated with increased risk of metabolic syndrome, specifically decreased HDL and impaired fasting glucose levels were the factors that increased association was found.
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Registered trials
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