Evidence map›Paper›PMID 32476679›Full record

ArticleReumatologia2020

Polymyalgia rheumatica following infective triggers or vaccinations: a different subset of disease?

Paolo Falsetti, Edoardo Conticini, Caterina Acciai, Caterina Baldi, Marco Bardelli, Stefano Gentileschi, Luca Cantarini, Bruno Frediani

Open access · diamondAbstract read
In one paragraph

Article in Reumatologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Polymyalgia Rheumatica Following Respiratory Syncytial Virus (RSV) Vaccination.European journal of case reports in internal medicine · 2024
    Article
  6. Article
  7. Observational
  8. Article
  9. Polymyalgia Rheumatica Following COVID-19 Vaccination.Internal medicine (Tokyo, Japan) · 2022
    Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Paolo FalsettiRheumatology Unit, University of Siena, Italy.
Edoardo ConticiniRheumatology Unit, University of Siena, Italy.
Caterina AcciaiNeurorehabilitation Unit, Arezzo Hospital, Italy.
Caterina BaldiRheumatology Unit, University of Siena, Italy.
Marco BardelliRheumatology Unit, University of Siena, Italy.
Stefano GentileschiRheumatology Unit, University of Siena, Italy.
Luca CantariniRheumatology Unit, University of Siena, Italy.
Bruno FredianiRheumatology Unit, University of Siena, Italy.
University of Siena · ITAzienda Usl 8 Arezzo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPolymyalgia rheumatica (PMR) is the commonest inflammatory disorder of the elderly; an association with environmental triggers and a deregulated immune response have been described. The aim of this study was to investigate the association of environmental triggers before the onset of PMR. MATERIAL AND

methodsThe database of 58 consecutive PMR patients recruited from a single rheumatology secondary care setting was retrospectively analyzed to investigate the frequency of environmental triggers and correlations with clinical characteristics, ultrasound and laboratory data.

resultsFifteen PMR patients (26%) described a connection with environmental agents: six PMR patients reported a vaccination, 4 reported a respiratory tract infection, 5 reported seasonal influenza before the onset of the disease. The model of multivariate linear regression which better predicted a shorter time to normalize inflammatory reactants (

conclusionsOur work describes a correlation between environmental triggers in PMR and higher CRP at diagnosis, faster response to therapy, and milder shoulder synovitis. We may suppose that these patients belong to a more specific subtype of PMR, in whom external stimuli, such as vaccination or infection, may lead to a deregulated response within the context of an impaired senescent immuno-endocrine system.

Indexed as

infectionpolymyalgia rheumaticaultrasoundvaccination

Identifiers

PMID32476679
PMCPMC7249527
OpenAlexW3027961469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.