Evidence map›Paper›PMID 32476555›Full record

ArticleEpigenetics2020

Estrogen-induced epigenetic silencing of

Jibran Sualeh Muhammad, Khuloud Bajbouj, Jasmin Shafarin, Mawieh Hamad

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 109 citations in OpenAlex.

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  10. [Deciphering cellular processes responding to lethality of 17Se pu = Chinese journal of chromatography · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jibran Sualeh MuhammadDepartment of Basic Medical Sciences, College of Medicine, University of Sharjah , Sharjah, United Arab Emirates.ORCID 0000-0002-9565-1062
Khuloud BajboujDepartment of Basic Medical Sciences, College of Medicine, University of Sharjah , Sharjah, United Arab Emirates.
Jasmin ShafarinIron Biology Group, Sharjah Institute for Medical Research, University of Sharjah , Sharjah, United Arab Emirates.
Mawieh HamadIron Biology Group, Sharjah Institute for Medical Research, University of Sharjah , Sharjah, United Arab Emirates.ORCID 0000-0002-6769-1091
University of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogen (E2) regulates hundreds of genes involved in cell metabolism and disrupts iron homoeostasis in various cell types. Herein, we addressed whether E2-induced epigenetic modifications are involved in modulating the expression of iron-regulatory genes. Epigenetic status of

Indexed as

ApoptosisCell ProliferationAntigens, CDDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BEstrogensFerritinsGene Expression Regulation, NeoplasticGene SilencingHep G2 CellsHumansLiver NeoplasmsMCF-7 CellsOxidoreductasesProtein-Arginine N-MethyltransferasesReceptors, TransferrinAntigens, CDCD71 antigenDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BEstrogensFerritinsFTH1 protein, humanOxidoreductasesPRMT5 protein, humanProtein-Arginine N-MethyltransferasesReceptors, TransferrinDNA methylationEstrogenHistone methylationIron-regulatory genesLiver cancer

Identifiers

PMID32476555
PMCPMC7678938
OpenAlexW3030458349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.