Evidence map›Paper›PMID 32476233›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Strategies for liver transplantation during the SARS-CoV-2 outbreak: Preliminary experience from a single center in France.

Xavier Muller, Gilles Tilmans, Quentin Chenevas-Paule, Fanny Lebossé, Teresa Antonini, Domitille Poinsot, Agnès Rode, Céline Guichon, Zoé Schmitt, Christian Ducerf and 3 more

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xavier MullerDepartment of Digestive Surgery and Transplantation, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.ORCID 0000-0002-8849-5495
Gilles TilmansDepartment of Digestive Surgery and Transplantation, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Quentin Chenevas-PauleDepartment of Digestive Surgery and Transplantation, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Fanny LebosséDepartment of Hepatology, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Teresa AntoniniDepartment of Hepatology, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Domitille PoinsotDepartment of Hepatology, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Agnès RodeDepartment of Radiology, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Céline GuichonDepartment of Intensive Care, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Zoé SchmittDepartment of Intensive Care, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Christian DucerfDepartment of Digestive Surgery and Transplantation, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.
Kayvan MohkamDepartment of Digestive Surgery and Transplantation, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.ORCID 0000-0002-9695-0902
Mickaël LesurtelDepartment of Digestive Surgery and Transplantation, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.ORCID 0000-0003-2397-4599
Jean-Yves MabrutDepartment of Digestive Surgery and Transplantation, University Hospital Croix Rousse, Hospices Civils de Lyon, University of Lyon I, Lyon, France.ORCID 0000-0002-5701-3588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplantation (LT) during the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is challenging given the urgent need to reallocate resources to other areas of patient care. Available guidelines recommend reorganizing transplant care, but data on clinical experience in the context of SARS-CoV-2 pandemic are scarce. Thus, we report strategies and preliminary results in LT during the peak of the SARS-CoV-2 pandemic from a single center in France. Our strategy to reorganize the transplant program included 4 main steps: optimization of available resources, especially intensive care unit capacity; multidisciplinary risk stratification of LT candidates on the waiting list; implementation of a systematic SARS-CoV-2 screening strategy prior to transplantation; and definition of optimal recipient-donor matching. After implementation of these 4 steps, we performed 10 successful LTs during the peak of the pandemic with a short median intensive care unit stay (2.5 days), benchmark posttransplant morbidity, and no occurrence of SARS-CoV-2 infection during follow-up. From this preliminary experience we conclude that efforts in resource planning, optimal recipient selection, and organ allocation strategy are key to maintain a safe LT activity. Transplant centers should be ready to readapt their practices as the pandemic evolves.

Indexed as

PandemicsPractice Guidelines as TopicAdultAgedComorbidityCOVID-19FemaleFollow-Up StudiesFranceHumansIntensive Care UnitsLiver FailureLiver TransplantationMaleMiddle AgedPrognosiscancer/malignancy/neoplasiaclinical decision-makingclinical research/practicediagnostic techniques and imaginginfection and infectious agents - viralliver transplantation/hepatologyorgan procurement and allocationrisk assessment/risk stratification

Identifiers

PMID32476233
PMCPMC7300692

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.