Evidence map›Paper›PMID 32476217›Full record

ArticleHead & neck2020

Impact of a tobacco treatment program on abstinence and survival rates among current smokers with head and neck squamous cell carcinoma.

Andrew T Day, Kristina R Dahlstrom, Rebecca Lee, Maher Karam-Hage, Erich M Sturgis

Abstract read
In one paragraph

Article in Head & neck, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic Review of Smoking Cessation Interventions for Smokers Diagnosed with Cancer.International journal of environmental research and public health · 2022
    Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Racial and Ethnic Disparities in Laryngeal Cancer Care.Journal of racial and ethnic health disparities · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew T DayDepartment of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-7187-4125
Kristina R DahlstromDepartment of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Rebecca LeeDepartment of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-5215-5977
Maher Karam-HageDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Erich M SturgisPopulation Science & Cancer Control, UT Southwestern Simmons Comprehensive Cancer Center, Dallas, Texas, USA.ORCID 0000-0002-1069-4822

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

backgroundApproximately one quarter of head and neck cancer (HNC) patients smoke cigarettes at the time of diagnosis. Despite HNC guideline recommendations to treat tobacco dependence, the effectiveness of treatment in this population is poorly described.

methodsThis retrospective cohort review evaluated 117 current smokers with p16-negative mucosal head and neck squamous cell carcinoma prospectively enrolled in a tobacco treatment program. Seven-day point prevalence tobacco abstinence rates at 9 months and survival outcomes were compared among abstinent and nonabstinent groups.

resultsMedian follow-up among survivors was 62.4 months. Forty percent of patients were abstinent at 9 months according to intention-to-treat analysis. After adjustment for age, comorbidity and site, abstinent stage I to II patients had a decreased risk of death compared to smoking stage I to II patients (HR 0.15, 95% CI 0.03-0.82).

conclusionsHigh cohort abstinence rates and favorable survival among abstinent patients with early-stage HNC confirm the importance of tobacco dependence treatment in this population.

Indexed as

Head and Neck NeoplasmsSmoking CessationTobacco ProductsHumansRetrospective StudiesSmokersSquamous Cell Carcinoma of Head and NeckSurvival Rateabstinencecigaretteshead and neck cancermucosal squamous cell carcinomaoutcomessmokingsurvivaltobaccotobacco dependencetobacco treatment

Identifiers

PMID32476217
PMCPMC8691203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.