ArticleMikrochimica acta2020
Colorimetric determination of cysteine by a paper-based assay system using aspartic acid modified gold nanoparticles.
Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 35 citations in OpenAlex.
- Development of a Semiquantitative Barcode Readout Approach for Paper-Based Analytical Devices (PADs) for Enzymatic HAnalytical chemistry · 2025Article
- An irreversible paper-based profluorescent nitroxide probe for the selective detection of ascorbic acid.RSC advances · 2023Article
- Recent Aptamer-Based Biosensors for CdBiosensors · 2023Review
- Enhancement of the Detection Performance of Paper-Based Analytical Devices by Nanomaterials.Molecules (Basel, Switzerland) · 2022Review
- Colorimetric determination of cysteine based on Au@Pt nanoparticles as oxidase mimetics with enhanced selectivity.Mikrochimica acta · 2021Article
- Nanozyme based on graphene oxide modified with FeMikrochimica acta · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
A method is described for cysteine (Cys) determination on paper-based analytical devices using aspartic acid modified gold nanoparticles (Asp-AuNPs). The Asp-AuNPs were characterized by their size, zeta potential, and UV-visible absorption spectrum. After the addition of Cys, it will interact with Asp-AuNPs selectively and leads to the aggregation of Asp-AuNPs. A color change from red to blue can be observed on the paper-based analytical devices. The results were recorded using a cell phone and subsequently analyzed using the Photoshop software. The ratiometric color intensity at red channel and blue channel (Red/Blue) increased linearly in the range 99.9-998.7 μM for Cys (R = 0.9984), and the limit of detection was 1.0 μM. The effects of assay conditions have been investigated and are discussed. The Cys concentration was determined as (0.27 ± 0.02 mM) in human plasma, and the recovery was from 99.2 to 101.1%. Graphical abstract Schematic representation of the paper-based assay system using aspartic acid modified gold nanoparticles (Asp-AuNPs). The ratiometric color intensity method was used for the cysteine (Cys) determination.
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