ReviewDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2021
Anastomotic leakage after esophagectomy for esophageal cancer: definitions, diagnostics, and treatment.
Review in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
131 citing papers in PubMed, 8 syntheses or guidelines pooled it, 193 citations in OpenAlex.
- International Society for Diseases of the Esophagus consensus on the diagnosis and treatment of anastomotic leak after esophagectomy.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026Guideline
- The effectiveness of intraoperative indocyanine green fluorescence imaging in preventing anastomotic leakage after minimally invasive esophagectomy for esophageal cancer: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- SAGES 2025 guidelines for fluorescence image-guided gastrointestinal surgery using indocyanine green.Surgical endoscopy · 2025Guideline
- VacStent as a novel therapeutic approach for esophageal perforations and anastomotic leaks- a systematic review of the literature.BMC surgery · 2025Pooled it
- Effects of Postoperative Complications on Overall Survival Following Esophagectomy: A Meta-Analysis Using the Restricted Mean Survival Time Analysis.Thoracic cancer · 2025Pooled it
- Biomarkers associated with anastomotic leakage after esophagectomy: a systematic review.Langenbeck's archives of surgery · 2025Pooled it
- Pooled it
- Effect of Enteral Immunonutrition in Patients Undergoing Surgery for Gastrointestinal Cancer: An Updated Systematic Review and Meta-Analysis.Frontiers in nutrition · 2022Pooled it
- Endoscopic vacuum therapy for anastomotic leakage after upper gastrointestinal surgery.Endoscopy · 2023Trial
- Outcomes of early fiberoptic bronchoscopic sputum aspiration and lavage after thoracoscopic and laparoscopic esophageal cancer surgery: a randomized clinical trial.Journal of cardiothoracic surgery · 2023Trial
- Performance of a consensus-based algorithm for diagnosing anastomotic leak after minimally invasive esophagectomy for esophageal cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023Trial
- Individualized Stent for Tracheal Fistula Complicating Tracheostomy Following Esophagectomy.Respirology case reports · 2026Article
- Institutional Learning Curve in Esophagectomy: Technical Standardization of Gastric Conduit Formation and Conduit-Related Outcomes in 187 Consecutive Patients.Journal of surgical oncology · 2026Article
- Indocyanine Green-Guided Decision-Making for Cervical Esophagogastric Anastomosis Using the Modified Collard Technique: Implementation and Temporal Stability in a Consecutive Cohort.World journal of surgery · 2026Article
- Detection of Anastomotic Leaks Following Esophagectomy with Cervical Anastomosis Using Drain Fluid Amylase Testing: A Retrospective Study in Taiwan.Journal of chest surgery · 2026Article
- Complications and survival after Ivor Lewis esophagectomy.BMC cancer · 2026Article
- Cervical Anastomotic Leakage After Minimally Invasive McKeown Esophagectomy in the SAFER Surgical System: Clinical Course and Predictors of Delayed Healing.Thoracic cancer · 2026Article
- Association of perioperative patient characteristics, intraoperative fluid management, and vasopressors with anastomotic leakage after Ivor-Lewis esophagectomy-a single center retrospective cohort.Surgical endoscopy · 2026Article
- Article
- Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anastomotic leakage is one of the most severe complications after esophagectomy and is associated with increased postoperative morbidity and mortality. Several projects ranging from small retrospective studies to large collaborations have aimed to identify potential pre- and perioperative risk factors and to improve the diagnostic processes and management. Despite the increase in available literature, many aspects of anastomotic leakage are still debated, without the existence of widely accepted guidelines. The purpose of this review is to provide a cutting edge overview of the recent literature regarding the definition and classification of anastomotic leakage, risk factors, novel diagnostic modalities, and emerging therapeutic options for treatment and prevention of anastomotic leakage following esophagectomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.