Evidence map›Paper›PMID 32475907›Full record

ArticleInternal medicine (Tokyo, Japan)2020

IgG4-related Autoimmune Hepatitis with a Suspected Drug-induced Etiology.

Hideaki Kawabata, Yukino Kawakatsu, Naonori Inoue, Yuji Okazaki, Daiki Sone, Katsutoshi Yamaguchi, Yuki Ueda, Misuzu Hitomi, Masatoshi Miyata, Shigehiro Motoi and 2 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hideaki KawabataDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Yukino KawakatsuDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Naonori InoueDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Yuji OkazakiDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Daiki SoneDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Katsutoshi YamaguchiDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Yuki UedaDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Misuzu HitomiDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Masatoshi MiyataDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Shigehiro MotoiDepartment of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.
Yasuyuki EnokiDepartment of Pathology, Kyoto Okamoto Memorial Hospital, Japan.
Tetsuhiro MinamikawaDepartment of Pathology, Kyoto Okamoto Memorial Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 69-year-old man was referred to our department with acute hepatitis. He had been newly treated with benidipine hydrochloride for two months. His blood test results were as follows: aspartate aminotransferase, 1,614 IU/L; alanine aminotransferase, 1,091 IU/L and anti-smooth muscle antibody, ×80. Needle liver biopsy specimen showed interface hepatitis with mainly lymphocytic infiltration and bridging fibrosis in the periportal area. Immunohistochemistry revealed lymphocytic infiltration positive for IgG4. We diagnosed him with IgG4-related AIH with an etiology that was suspected of being drug-induced. Oral prednisolone was started and then tapered after achieving biochemical remission. Hepatitis recurred after the cessation of steroids; however, remission was achieved with ursodeoxycholic acid.

Indexed as

AgedAnti-Inflammatory AgentsCholagogues and CholereticsHepatitis, AutoimmuneHepatitis, ChronicHumansImmunoglobulin GJapanMaleNifedipinePrednisoloneTreatment OutcomeUrsodeoxycholic AcidAnti-Inflammatory AgentsCholagogues and CholereticsImmunoglobulin GNifedipinePrednisoloneUrsodeoxycholic Acidautoimmune hepatitisdrug-inducedIgG4

Identifiers

PMID32475907
PMCPMC7332635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.