Observational studySurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2020
Change in predicted 10-year and lifetime cardiovascular disease risk after Roux-en-Y gastric bypass.
Observational study in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Differential effects of bariatric surgery and lifestyle interventions on plasma levels of Lp(a) and fatty acids.Lipids in health and disease · 2022Trial
- Baseline metabolomic profile as potential biomarker for weight change after Roux-en-Y gastric bypass (RYGB) surgery.Research square · 2025Article
- Investigating a New Way to Assess Metabolic Risk in Pregnant Females with Prior RYGB Surgery.Nutrients · 2024Article
- An Assessment of the Effect of Bariatric Surgery on Cardiovascular Disease Risk in the Chinese Population Using Multiple Cardiovascular Risk Models.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- A 7-Year Study of the Durability of Improvements in Pain, Physical Function, and Work Productivity After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy.JAMA network open · 2022Article
- Change in C-reactive protein after Roux-en-Y gastric bypass through 7 years of follow-up.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2022Article
- Comparative effectiveness of gastric bypass and sleeve gastrectomy on predicted 10-year risk of cardiovascular disease 5 years after surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2022Article
- Glycemic Patterns Are Distinct in Post-Bariatric Hypoglycemia After Gastric Bypass (PBH-RYGB).The Journal of clinical endocrinology and metabolism · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLong-term changes in cardiovascular disease (CVD) risk after bariatric surgery are not well characterized.
objectiveTo report sex-specific changes in CVD risk after Roux-en-Y gastric bypass surgery (RYGB).
settingObservational cohort study at ten hospitals throughout the United States.
methodsBetween 2006 and 2009, 1770 adults enrolled in a prospective cohort study underwent RYGB at 1 of 10 U.S. hospitals. Research assessments were conducted presurgery and annually postsurgery over 7 years. Sex specific-predicted 10-year and lifetime CVD risk were calculated using the Framingham10-year and lifetime risk scores, Framingham-body mass index, and atherosclerotic CVD scoring algorithms among participants with no history of CVD. Of 1566 eligible participants, 1234 (75.9%) with CVD risk determination pre- and postsurgery were included (1013 females, 221 males).
resultsBased on the Framingham10-year and lifetime risk scores, the percentage of females with predicted high (>20%) 10-year CVD risk declined from presurgery (6.5% [95% confidence interval: 6.7-7.5]) to 1 year postsurgery (1.0% [95% confidence interval: .8-1.2]; P < .001), then increased 1 to 7 years postsurgery (to 2.8% [95% confidence interval: 1.6-3.3]; P = .003), but was lower 7 years postsurgery versus presurgery (P < .001). Time trends for percentage of high-risk participants and mean CVD risk scores were similar for both sexes and other evaluated CVD risk scores. For example, among males mean lifetime atherosclerotic CVD score declined from presurgery to 1 year postsurgery, then increased 1 to 7 years postsurgery. However, there was a net decline from presurgery (P < .001).
conclusionAmong both females and males, predicted 10-year and lifetime CVD risk was substantially lower 7 years post RYGB than presurgery, suggesting RYGB surgery can lead to sustained improvements in short- and long-term CVD risk.
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