Evidence map›Paper›PMID 32475422›Full record

ArticlePoultry science2020

POMC gene expression, polymorphism, and the association with reproduction traits in chickens.

K Liu, Y Y Wen, H H Liu, H Y Cao, X Y Dong, H G Mao, Z Z Yin

Open access · goldAbstract read
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Polymorphisms within theFoods (Basel, Switzerland) · 2024
    Article
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

K LiuAnimal Science College, Zhejiang University, Zijingang Campus, Hangzhou, China 310058.
Y Y WenAnimal Science College, Zhejiang University, Zijingang Campus, Hangzhou, China 310058.
H H LiuAnimal Science College, Zhejiang University, Zijingang Campus, Hangzhou, China 310058.
H Y CaoAnimal Science College, Zhejiang University, Zijingang Campus, Hangzhou, China 310058.
X Y DongAnimal Science College, Zhejiang University, Zijingang Campus, Hangzhou, China 310058.
H G MaoAnimal Science College, Zhejiang University, Zijingang Campus, Hangzhou, China 310058.
Z Z YinAnimal Science College, Zhejiang University, Zijingang Campus, Hangzhou, China 310058. Electronic address: yzhzh@zju.edu.cn.
Zhejiang University · CN

Funding

Investigation of metabolites related to manganese exposureF31ES027304 · NIEHS · UNIVERSITY OF WASHINGTON · PI BAKER, MARISSA GAYL · 2016 to 2017
$61k
NIEHS NIH HHS 27304C2054
6 · The paper itself

Abstract

Reproduction trait is one of the most important economic traits in poultry industry. This study was aimed to investigate the mRNA expression levels, single nucleotide polymorphisms (SNP) of POMC gene, and the association with reproduction traits in chickens. Five SNP (g.958 G > A, g.1374 G > C, g.1393 G > A, g.1817 C > T, and g.1918G > A) were detected in introns of POMC gene in 317 Zhenning yellow chickens. Association analysis revealed that g.958 G > A and g.1817 C > T showed significantly associations with fertilization rate, hatching rate of hatching eggs, and hatching rate of fertilized eggs in chickens. Simultaneously, g.1374 G > C and g.1918G > A were both associated with egg weight at 300 D of age (P < 0.05). The SNP of g.958 G > A, g.1393 G > A, and g.1817 C > T were all associated with E2 hormone levels (P < 0.05). The result of mRNA expression levels in different tissues showed that POMC mRNA expression level in the pituitary was higher than those in the other tissues and varied in different genotypes. In conclusion, the results in this study provided new evidences that polymorphisms of the POMC gene have potential effects on reproduction traits in chickens. The 5 SNP detected in this study could be potential markers for improving reproduction traits in chickens.

Indexed as

Gene ExpressionPolymorphism, GeneticAnimalsAvian ProteinsChickensGenome-Wide Association StudyPro-OpiomelanocortinReproductionRNA, MessengerAvian ProteinsPro-OpiomelanocortinRNA, MessengerchickenexpressionpolymorphismsPOMCreproduction traits

Identifiers

PMID32475422
PMCPMC7597669
OpenAlexW3011533580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.