Evidence map›Paper›PMID 32474936›Full record

ArticleJournal of periodontology2021

Transcriptional activity of vitamin D receptor in human periodontal ligament cells is diminished under inflammatory conditions.

Alice Blufstein, Christian Behm, Barbara Kubin, Johannes Gahn, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov

Open access · hybridAbstract read
In one paragraph

Article in Journal of periodontology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. The Role of Vitamin DNutrients · 2026
    Review
  2. Article
  3. Vitamin DInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Effect of vitamin DJournal of periodontal research · 2021
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alice BlufsteinDepartment of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
Christian BehmDepartment of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
Barbara KubinDepartment of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
Johannes GahnDepartment of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
Andreas MoritzDepartment of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
Xiaohui Rausch-FanDepartment of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
Oleh AndrukhovDepartment of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough vitamin D

methodsCells isolated from six different donors were treated with either 1,25(OH)

resultsThe vitamin D

conclusionsThis study indicates that the transcriptional activity of VDR is diminished under inflammatory conditions, which might mitigate the effectiveness of vitamin D

Indexed as

Periodontal LigamentReceptors, CalcitriolCholecalciferolHumansPorphyromonas gingivalisVitamin DCholecalciferolReceptors, CalcitriolVDR protein, humanVitamin Dinflammationmesenchymal stem cellsperiodontal ligamentVDRvitamin D

Identifiers

PMID32474936
PMCPMC7891446
OpenAlexW3028598440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.