Evidence map›Paper›PMID 32474889›Full record

ArticleMolecular diversity2021

Indole-fused spirochromenes as potential anti-tubercular agents: design, synthesis and in vitro evaluation.

Ashok Dogamanti, Pamula Chiranjeevi, Vikas Kumar Aamate, Siva Krishna Vagolu, Dharmarajan Sriram, Sridhar Balasubramanian, Madderla Sarasija

Abstract read
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In one paragraph

Article in Molecular diversity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashok DogamantiGreen and Medicinal Chemistry Lab, Department of Chemistry, Osmania University, Hyderabad, Telangana State, 500 007, India. ashokdou@gmail.com.
Pamula ChiranjeeviGreen and Medicinal Chemistry Lab, Department of Chemistry, Osmania University, Hyderabad, Telangana State, 500 007, India.
Vikas Kumar AamateGreen and Medicinal Chemistry Lab, Department of Chemistry, Osmania University, Hyderabad, Telangana State, 500 007, India.
Siva Krishna VagoluDepartment of Pharmacy, Birla Institute of Technology and Science - Pilani, Hyderabad Campus, Jawahar Nagar, Hyderabad, Telangana State, 500 078, India.
Dharmarajan SriramDepartment of Pharmacy, Birla Institute of Technology and Science - Pilani, Hyderabad Campus, Jawahar Nagar, Hyderabad, Telangana State, 500 078, India.
Sridhar BalasubramanianX-Ray Crystallography Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500 007, India.
Madderla SarasijaDepartment of Chemistry, Satavahana University, Karimnagar, Telangana State, 505001, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As part of an ongoing effort to develop new anti-tubercular agents, a series of novel indole-fused spirochromene hybrids (7a-l) were efficiently synthesized in excellent yields by the popular 'Fisher-Indole synthesis' approach. The structure elucidation of the target compounds was carried out by different spectral techniques including

Indexed as

Antitubercular AgentsDrug DesignIndolesMicrobial Sensitivity TestsMycobacterium tuberculosisSpiro CompoundsBenzopyransChemistry Techniques, SyntheticStructure-Activity RelationshipAntitubercular AgentsBenzopyransIndolesSpiro CompoundsIndoleIndole-fused spirochromeneMycobacterium tuberculosisSpirochromeneX-ray crystal

Identifiers

PMID32474889

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.