Evidence map›Paper›PMID 32474711›Full record

ArticleLangenbeck's archives of surgery2020

Novel endoscopic marking clip equipped with resin-conjugated fluorescent indocyanine green during laparoscopic surgery for gastrointestinal cancer.

Tsutomu Namikawa, Jun Iwabu, Motoi Hashiba, Masaya Munekage, Sunao Uemura, Takayoshi Yamada, Hiroyuki Kitagawa, Hiroshi Mizuta, Ken Okamoto, Kazushige Uchida and 3 more

Abstract read
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In one paragraph

Article in Langenbeck's archives of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Tsutomu NamikawaDepartment of Surgery, Kochi Medical School, Nankoku, Kochi, Japan. tsutomun@kochi-u.ac.jp.ORCID http://orcid.org/0000-0001-8971-404X
Jun IwabuDepartment of Surgery, Kochi Medical School, Nankoku, Kochi, Japan.
Motoi HashibaDepartment of Gastroenterology and Hepatology, Kochi Medical School, Nankoku, Kochi, Japan.
Masaya MunekageDepartment of Surgery, Kochi Medical School, Nankoku, Kochi, Japan.
Sunao UemuraDepartment of Surgery, Kochi Medical School, Nankoku, Kochi, Japan.
Takayoshi YamadaDepartment of Gastroenterology and Hepatology, Kochi Medical School, Nankoku, Kochi, Japan.
Hiroyuki KitagawaDepartment of Surgery, Kochi Medical School, Nankoku, Kochi, Japan.
Hiroshi MizutaDepartment of Gastroenterology and Hepatology, Kochi Medical School, Nankoku, Kochi, Japan.
Ken OkamotoDepartment of Human Health and Medical Sciences, Kochi Medical School, Nankoku, Kochi, Japan.
Kazushige UchidaDepartment of Gastroenterology and Hepatology, Kochi Medical School, Nankoku, Kochi, Japan.
Takayuki SatoCenter for Photodynamic Medicine, Kochi Medical School, Nankoku, Kochi, Japan.
Michiya KobayashiDepartment of Human Health and Medical Sciences, Kochi Medical School, Nankoku, Kochi, Japan.
Kazuhiro HanazakiDepartment of Surgery, Kochi Medical School, Nankoku, Kochi, Japan.
Kochi Medical School Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIntraoperative identification of the cancer location is often difficult to conduct during laparoscopic surgery, especially in early-stage cancers. This study aimed to investigate the feasibility and accuracy of a novel endoscopic clip resin-conjugated fluorescent indocyanine green during laparoscopic surgery for gastrointestinal cancer.

methodsPreoperative placement of endoscopic marking clips equipped with resin-conjugated fluorescent indocyanine green was performed to determine the resection margin in eight patients with gastrointestinal cancer. During laparoscopic surgery, a dedicated laparoscopic system with a xenon light source was used to detect fluorescence. The evaluation determined whether the fluorescent from the clips was visualized during laparoscopic surgery.

resultsFluorescent signal emitted from ICG in the resin of the clips was detected in six patients from the outer layer of the serosal surfaces of the gastrointestinal tract, and the clips aided in accurate resection line of the organ. There were no significant differences of age, gender, and BMI between the patients in whom we could and could not detect ICG fluorescence.

conclusionsThe results demonstrated the usefulness of a novel clip-equipped fluorescent resin, which is a promising diagnostic tool to detect accurate tumor location during laparoscopic surgery.

Indexed as

Fluorescent DyesIndocyanine GreenOptical ImagingAdultAgedAged, 80 and overFeasibility StudiesFemaleGastrointestinal NeoplasmsHumansLaparoscopyMaleMiddle AgedRetrospective StudiesFluorescent DyesIndocyanine GreenFluorescence-guided surgeryFluorescent resinIndocyanine greenLaparoscopic surgeryNear-infrared fluorescence

Identifiers

PMID32474711
OpenAlexW3030588293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.